Intern, Downstream Production

**Intern, Downstream production]** - Hummingbird Bioscience**

Full-time internship - [SG] based location

**ABOUT HUMMINGBIRD BIOSCIENCE**

Hummingbird Bioscience is a precision biotherapeutics company discovering and developing transformative biologics for hard-to-treat diseases. To address key challenges with current antibody-drug conjugate (ADC) therapies, Hummingbird Bioscience is building a pipeline of next-generation ADCs using its proprietary antibody discovery and linker/payload platforms. The company has a pipeline of ADCs in preclinical development and other novel biologics including monoclonal antibodies, HMBD-001 (anti-HER3 mAb) and HMBD-002 (anti-VISTA mAb) in Phase I and a recently out-licensed ADC (HMBD-501) that will enter the clinic this year. The Hummingbird Bioscience approach combines computational and systems biology with wet lab drug discovery in a multi-disciplinary, collaborative environment spanning initial discovery through clinical development. The company harnesses this integrated approach across target identification and patient selection, enabling the team to increase the efficiency of translating novel scientific insights while reducing the inherent risk in drug discovery and development. At Hummingbird Bioscience, the commitment to rigorous science, teamwork, and intellectual integrity underpins our passion to accelerate the journey of new drugs from concept to clinic.

**ABOUT THE ROLE**

We are looking for an intern to join the downstream process development team to support protein purification and bioconjugation work. This role provides the opportunity for the intern to understand the workflows associated with the production of antibodies and antibody-drug conjugates.

**KEY RESPONSIBILITIES**
- Assist in the purification of antibodies and antibody drug conjugates using AKTA systems, such as affinity chromatography, ion exchange chromatography
- Assist in filtration activities, such as depth filtration, viral filtration, ultrafiltration/diafiltration
- Assist in the conjugation of linker payloads to antibodies
- Support exploratory data analysis and data mining to derive actionable insights
- Support the implementation of data-driven models to identify trends, optimise processes, and enhance product quality
- Support other ad-hoc tasks, such as buffer preparation, sample labelling, running of SDS-PAGE gel
- Maintain timely and accurate data records

**ESSENTIAL QUALIFICATIONS**
- Currently enrolled in a Bachelor’s or Master’s Program in Chemistry, Biochemistry, Biology or related fiel
- Basic laboratory experience and knowledge in protein purification techniques. Training will be provided
- Willingness to learn new skills
- Able to adapt to fast-paced environment

**DESIRABLE QUALIFICATIONS**
- Familiarity with Python and/or R

**OUR MISSION & VALUES**

Our fast-growing biotechnology company is committed to discovering and developing important new drugs for cancer and autoimmune diseases, and living by our values: Excellence, Determination, Teamwork, Intellectual Integrity and Audacity.

**JOIN US AT THE FRONTIER OF DRUG DISCOVERY AND DEVELOPMENT**

We are looking for passionate and motivated individuals committed to solving important, complex problems. As an intern, you will have the opportunity to learn from a multi-disciplinary team and work towards transforming the therapeutic landscape for hard-to-treat diseases. We are committed to the personal and professional development of our team and offer robust learning and development programs. Hummingbird Bioscience understands the need for flexibility for our team and offers a generous paid time off program with flexibility to support employees through different life stages. We invest in our team’s health and offer a comprehensive and holistic employee assistance program. We foster a more collaborative, productive, and sociable culture with on-site lunches and snacks. Finally, we believe in creating social impact beyond our business through corporate social responsibility initiatives.
- Hummingbird Bioscience is firmly committed to Equal Employment Opportunity (EEO) and to compliance with all Singapore and US federal, state and local laws and/or guidelines that prohibit employment discrimination on the basis of age, race, color, gender, sexual orientation, gender identity, ethnicity, national origin, citizenship, religion, genetic carrier status, disability, pregnancy, childbirth or related medical conditions, marital status, protected veteran status and other protected classifications._