Bioinformatician (Structural Biology)

**Responsibilities**:
DSO National Laboratories (DSO) is Singapore’s largest defence research and development (R&D) organisation, with the critical mission to develop technological solutions to sharpen the cutting edge of Singapore's national security. At DSO, you will develop more than just a career. This is where you will make a real impact and shape the future of defence across the spectrum of air, land, sea, space and cyberspace.

The Defence Medical & Environmental Research Institute (DMERI) builds up technological capabilities for the protection against chemical and biological warfare agents. It also conducts research and development into combat care, human effectiveness, bio
- technology and bio-engineering to enhance the safety, survivability and performance of our national forces in hostile battlefield environment.

People are DSO’s greatest asset. You will get to realise your career aspirations and develop your own niche either as a deep technical expert or a leader in the team. With frequent career dialogues and a robust training and development framework, we will provide you with the necessary development tools for you to reach your potential. You will also be recognised and rewarded through competitive remuneration packages and scholarship opportunities.

Bioinformatician (Structural Biology)

In this role, you will:

- Develop solutions to detect and characterize pathogens using genomics and computational biology
- Perform in silico protein structure prediction from pathogens of interest, predict functions, identify targets of therapeutic potential and design therapeutic solutions
- Identify, evaluate and recommend appropriate computational software and hardware requirements to enable timely data analysis
- Develop and validate analytic pipelines for NGS data analysis, protein structure prediction, therapeutic target identification and efficacy assessment
- Setup, update, maintain and ensure smooth running of data analysis systems, including databases
- Generate reports and presentation materials to update research findings

**Requirements**:

- Degree / Masters / PhD in Bioinformatics / Computational Biochemistry / Computational Biology
- Familiarity with Linux operating systems, scripting, installing programs and packages for bioinformatics
- Demonstrated experience with Python, R, or similar programming languages
- Working knowledge of common biological data analysis tools and databases, including that for NGS data analysis, protein structure modelling, molecular docking and molecular dynamics
- Knowledge and experience with biological database creation and management
- Motivated individual with keen interest in R&D and willingness to self-learn
- Good communication and writing skills
- Able to work both independently and in a team