Senior Research Officer/technologist

1 week ago

Singapore National Cancer Centre Singapore Full time

We are looking for a highly motivated and talented individual with passion in cancer genomics, biology and radiation research to join the Tan Chin Tuan Laboratory of Optical Imaging, Photodynamic and Proton Therapy - Precision Radiation Oncology Programme (PROP). The scope of the projects conducted under the premise of PROP includes 1) early and late-phase clinical trials; 2) cancer genomics and data science; and 3) translational cancer and radiation biology. You will be mainly working with the Principal Investigator (PI) and the research teams under Theme 2. The projects involve studying cancer genomics of two main cancers, nasopharyngeal and prostate cancer, and the development of risk stratification models or identification of novel biomarkers for radioresistance. Samples from consented patients will be used for next generation sequencing and/or microarray to generate “big data” for further analysis by our data scientists. You will be involved in inter-departmental collaborations with oncologists, pathologists, scientists, and local and international collaborators.

You will participate in the following activities:

- Process multi-omics molecular profiling of patient samples, including next generation sequencing, microarray analysis, etc.
- Maintain a complete and updated biobank and database of collected patient samples and perform QA/QCs to ensure excellent and consistent sample and data quality.
- Design and optimise new experiment protocols when necessary, e.g. functional validation of biomarkers.
- Lead and mentor junior staff in sample processing, experiments and database updates.
- Actively engage internal clinical and data science teams as well as external collaborators to ensure alignment with overall research goals.
- Participate in research activities, lab meetings/presentations, manuscript preparations and audits.
- Maintain inventory and purchase reagents, consumables and equipment when required.

**Auto req ID**
- 10010BR**Job Requirements**
- Diploma/B.Sc. degree in Biomedical/Life Sciences, or related fields.
- At least 3 years of research experience in molecular biology is necessary.
- Previous experience in cryosectioning, paraffin sectioning, IHC staining, H&E staining, blood sample processing, DNA/RNA extraction for next generation sequencing will be a plus.
- Prioritises proper handling, processing and documentation of patient samples; must be comfortable with handling blood or tissue samples.
- Strong technical wet lab skills and meticulous.
- Leadership, strong initiative and good communications skills are necessary.
- Good memory, strong organization and meticulous in database and biobank management.
- Analytical, self-confident and mature personality.
- Responsible and passionate about oncology clinical research.
- Able to work both independently and with other team members under pressure and tight deadlines.

**Job Category**
- Research**Job Function**
- Laboratory, Life Sciences, Research & Development, Research / Survey Services**Employment Type**
- Contract Full Time**Location**
- Singapore**Education Level**
- Bachelor’s Degree (Hons), Bachelors Degree, Diploma

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