Senior Principal Investigator

3 days ago


Singapore RMA CONTRACTS PTE. LTD. Full time

The position is for a Senior Principal Investigator (Consultant) for a National Medical Research Council (NMRC)-funded project in the area of neuro-metabolism and signal transduction pathway dysfunctions that underly dopaminergic neuronal death in Parkinson's Disease (PD).

Requirement for the Senior Principal Investigator:
1. An established expert in the field of Protein kinase biochemistry in this project focusing on the PD-associated kinase LRRK2 - that is causative for the most common inherited form of PD.

2. A working understanding of the role of Rho-family GTPases (Ras-like cytoskeleton regulators), in particular the proteins Miro1 /2 that regulate mitochondrial movement and dynamics inside neurons (or other cell types).

3. A track record in structural biology with publications in the area of protein-protein interactions, in this project the binding between Rho GTPases (when active) and their ‘effector’ proteins that serve to transmit signals to downstream targets.

A proven record in successfully writing, submitting and revising original research papers in relevant areas for top tier (10%) International Biomedical journals.

Susan Teo

Senior Consultant

**RMA Consultants Pte Ltd**

**EA License No. 93C4403**

**EA Regn. No. R1328587


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