Research Assistant, Population and Global Health LKCMedicine

The Lee Kong Chian School of Medicine (LKCMedicine) trains doctors who put patients at the centre of their exemplary care. The School, which offers both undergraduate and graduate programmes, is named after local philanthropist Tan Sri Dato Lee Kong Chian. Established in 2010 by Nanyang Technological University, Singapore, in partnership with Imperial College London, LKCMedicine aims to be a model for innovative medical education and a centre for transformative research. The School's primary clinical partner is the National Healthcare Group, a leader in public healthcare recognised for the quality of its medical expertise, facilities and teaching. The School is transitioning to an NTU medical school ahead of the 2028 successful conclusion of the NTU-Imperial partnership to set up a Joint Medical School. In August 2024, we welcomed our first intake of the NTU MBBS programme, that has been recently enhanced to include themes like precision medicine and Artificial Intelligence (AI) in healthcare, with an expanded scope in the medical humanities. Graduates from the five-year undergraduate medical degree programme will have a strong understanding of the scientific basis of medicine, with an emphasis on technology, data science and the humanities.

The PRECISE-SG100K is a landmark population cohort study of 100,000 Singaporeans of diverse ethnic background. The cohort has completed recruitment, and consists of whole genome sequences, comprehensive behavioral, phenotypic, and multi-omic data, and electronic health record linkage.  The study represents a state-of-the art platform for researchers to understand the etiology and pathogenesis of diverse disease outcomes in Asia, and to generate insights that have the potential to improve health outcomes for Asian populations globally.

The PRECISE-SG100K study is led by Professor John Chambers, the Toh Kian Chui Professor of Cardiovascular Epidemiology and Programme Director of the Population and Global Health Research Programme at Lee Kong Chian School of Medicine (LKCMedicine), Nanyang Technological University. Professor Chambers is also the Chief Scientific Officer for the National Precision Medicine Programme. The group research programme aims to identify the molecular mechanisms underlying diabetes and premature cardiovascular disease in Asian populations, and to translate these findings into new approaches for improved prevention and early detection of these major chronic diseases.

We are seeking a Research Assistant to support large-scale genomic data analysis and the generation of community resources for PRECISE-SG100K. The role involves pipeline development, data analysis, and documentation of analytical protocols, working within a leading interdisciplinary team of epidemiologists, geneticists, and computational biologists.

The appointee will play a key role in supporting both Professor Chambers' and the team, mainly in, but not limited to, the following roles:

• Developing and implementing pipelines for quality control and analysis of data.

• Conducting regular literature review to stay up-to-date on best practices.

• Contributing to the writing of publications in peer-reviewed journals, and presenting at international conferences.

• Maintain accurate and complete documentation of analysis

• Assist in co-ordination of project-related meetings, taking down summary of meeting, etc.

• Undertake any other duties relevant to the programme of research.

Key Competencies and Requirements:

• Minimum qualifications: Bachelor's degree in biomedical sciences, biotechnology or related fields.

• Experience analyzing large-scale population data.

• Experience using R, python, and bash.

• Strong communication (oral and written) and interpersonal skills as well as the ability to work in a team environment.

• Fluent in spoken and written English.