Senior Manager, Technology Transfer

6 days ago

Singapore General Hospital Singapore General Hospital Full time $120,000 - $180,000 per year

Job Responsibilities

1. Technical and Scientific Leadership

  • Support the technology transfer of new cell and gene therapy processes from collaborators in SingHealth to a GMP environment - Namely ACTRIS (Advanced Cell Therapy and Research Institute, Singapore).
  • Perform facility fit and gap assessment for introduction of new projects, including evaluating suitable materials, equipment and technology platforms.
  • Provide technical support for aseptic process simulations, process troubleshooting and investigations during process validation and clinical manufacturing,

2. Liaison and Cross-Functional Communication

  • Serve as the primary point of contact between SingHealth PIs/collaborators and ACTRIS GMP team to troubleshoot and resolve complex challenges
  • Work with suitable partners (e.g. ASTAR) and clinical collaborators to translate research protocols into actionable GMP processes.

3. Regulatory and Quality Support

  • Support the preparation and review of Chemistry, Manufacturing, and Controls (CMC) documentation, Master Batch Records (MBRs), Validation Protocols and Standard Operating Procedures (SOPs) to ensure GMP compliance.
  • Support discussion with regulatory bodies (eg. HSA) to facilitate clinical trial reviews and approvals.

4. Team and Stakeholder Management

  • Work closely with multidisciplinary teams, fostering collaboration across clinical and research functions.
  • Train and mentor junior team members to support technology transfer of new projects.

Job requirements:

  • Bachelor's degree in biomedical science or related studies.
  • Experience in working in an GMP facility and has experience in manufacturing in a GMP setting
  • Familiar with GMP processes and validation runs and writing SOPs for GMP processes.
  • Leadership skills - past experience in managing and leading a team
  • Good communicator and understand cell therapy lingo in clinical trial, scientific and technological aspects.

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