4d Tissues Laboratory Manager

REVIVO BioSystems is an innovative and customer-oriented company founded by a team of engineers and

biologists, with many years of experience in biomedical engineering, cell cultures, microfluidics and tissue

engineering. The company is aiming to become the Asian and global leading provider of enabling technologies

and services for _ex vivo _and _in vitro _testing of chemicals, ingredients, cosmetic formulations and therapeutics. Our

goal is to deliver products and services with unmatched quality, consistency, reproducibility, and ease-of-use. We

are on a fast growing trajectory and are looking to expand our organisation to further support the company’s

expansion, ambitious sales growth, and build more opportunities to make the world a more sustainable and

ethical place.

**_____________________________________**

Our organ-on-chip laboratory is looking for a Laboratory Manager who is highly motivated and has

either a recent Ph.D. or considerable experience in designing and supervising the execution of

mentoring research staff, and maintaining laboratory equipment and documentation. The person in this

role contributes a high level of technical expertise to the day to day scientific activities of REVIVO

BioSystems’ laboratory and is responsible for executing regulatory and non-regulatory _ex vivo _and _in_
- vitro _studies to GLP compliance, R&D projects, analytical measurements and assays, while guaranteeing

timely completion of all associated documentation and test reports.

The Laboratory Manager also plays a leading practical role in the setup of new test methods in the

laboratory, trouble-shooting technical issues, and overviewing the laboratory equipment and assets.

This is a crucial role for the development of REVIVO BioSystems’ R&D and operational capabilities, also

by collaborating with technical specialists and clients. The Laboratory Manager is encouraged to

research new ideas and will actively participate in meetings with clients to identify their needs and

provide adequate and innovative research proposals. As such, the individual in this position must stay

up to date with developments in the field of _in vitro _safety and efficacy, 3D cell cultures,

organ-on-a-chip, and put forward new ideas, methods and procedures.

The Research Scientist works closely with the company’s R&D and Testing Services team and is

accountable to the Head of _Ex Vivo _and _In Vitro _Testing.

**KEY ACCOUNTABILITIES/RESPONSIBILITIES**
- Design and supervise the execution of experiments using cell culture techniques (static or in

microfluidic system) to grow and maintain tissues for tests.
- Perform _in vitro _testing using tissue-on-chip models to investigate the effects of various

substances on skin cells.
- Play a leading practical role in the set up of new _ex vivo _and _in vitro _tests and actively

contribute to R&D projects.
- Deliver work to a high scientific standard and, where appropriate, in compliance with Good

Laboratory Practice (GLP) and with respect to Good Documentation Practice (GDP).
- Manage laboratory activities, including experimental design, execution, and data analysis.
- Experience in cloning and molecular biology and cloning is an advantage.
- Mentor research staff, including training and supervising laboratory technicians and

undergraduate students.
- Maintain laboratory equipment and protocols, including routine maintenance and

troubleshooting.
- Report any technical problems, study deviations or errors to the Head of _Ex Vivo _and _In Vitro_
- _Testing and other colleagues as appropriate.
- Troubleshoot technical issues with the support of the R&D and Testing Services teams.
- Process, analyse and present experimental data and results using statistical methods and

imaging in a timely way.
- Keep accurate and up-to-date laboratory records, including experimental protocols, data

sheets, and reports.
- Draft, update and maintain standard operating procedures, test methods and protocols

compliant to GLP.
- Participate in lab meetings and prepare research publications and presentations
- Ensure compliance with laboratory safety procedures and regulations to maintain a safe and

clean laboratory environment.

**MINIMUM REQUIREMENTS - EDUCATION AND EXPERIENCE**
- M.Sc. or Ph.D. in Biology, Cell Biology, Biochemistry or a related Life Science field, with

expertise in cell culture techniques,
_in vitro _testing and tissue engineering. Experience in
- skin-on-chip or other organ-on-chip models would be appreciated but not critical.
- Experience with 3D cell cultures, ELISA assays, histological processing and HPLC
- Excellent writing skills for scientific publications and conference proceedings, and strong

presentation skills.
- Strong organizational and time-management skills, with the ability to prioritize multiple tasks

and meet deadlines.
- Familiarity with Good Laboratory Procedures is a plus.
- Hands-on experience with OECD Test Guidelines and standard safet