Bioinformatician (Structural Biology)

2 weeks ago

Singapore DSO National Laboratories Full time

**Responsibilities**:
DSO National Laboratories (DSO) is Singapore’s largest defence research and development (R&D) organisation, with the critical mission to develop technological solutions to sharpen the cutting edge of Singapore's national security. At DSO, you will develop more than just a career. This is where you will make a real impact and shape the future of defence across the spectrum of air, land, sea, space and cyberspace.

The Defence Medical & Environmental Research Institute (DMERI) builds up technological capabilities for the protection against chemical and biological warfare agents. It also conducts research and development into combat care, human effectiveness, bio
- technology and bio-engineering to enhance the safety, survivability and performance of our national forces in hostile battlefield environments.

People are DSO’s greatest asset. You will get to realise your career aspirations and develop your own niche either as a deep technical expert or a leader in the team. With frequent career dialogues and a robust training and development framework, we will provide you with the necessary development tools for you to reach your potential l. You will also be recognised and rewarded through competitive remuneration packages and scholarship opportunities.

Bioinformatician (Structural Biology)

In this role, you will:

- Be part of a team to develop solutions to detect and characterise pathogens using genomics and computational biology
- Perform in silico protein structure prediction from pathogens of interest, predict functions, identify targets of therapeutic potential and design therapeutic solutions
- Identify, evaluate and recommend appropriate computational software and hardware requirements to enable timely data analysis
- Develop and validate analytic pipelines for protein structure protection and therapeutic target identification
- Set-up, update, maintain and ensure smooth running of data analysis systems, including databases
- Generate reports and presentation materials to update research findings

**Requirements**:

- PhD / Master’s / Bachelor’s Degree in Bioinformatics, Computational Biology or Information Technology, preferably with 1 to 3 years of relevant experience
- Familiarity with Linux operating systems, bash scripting and installing programs and packages
- Knowledge and experience with analysis of NGS data
- Experience in protein structure modelling and small molecule docking
- Demonstrated experience with Python, R, or similar programming languages
- Working knowledge of common biological data analysis tools and databases, including that for protein structure modelling and molecular dynamics
- Knowledge and experience with biological database creation and management
- Good communication and writing skills
- Able to work both independently and as a team
- Motivated individual with keen interest in genomics and willingness to self-learn

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