Head of Manufacturing Excellence

**Job Title: Head of Manufacturing Excellence**
**Location: Woodlands, Singapore**

**Reporting to: Head of Manufacturing**

**About the role**:
The Head of Manufacturing Excellence is responsible to ensure products manufactured in Takeda Singapore meet both patients’ requirements and supply requirements for the products. The individual will provide leadership to a diverse team and synergize activities across different cross-functional teams to enable day to day production support. The individual will ensure EHS and cGMP compliance in his department, implement life cycle improvements for plant processes and introduce new products to the plant. As part of the site’s Operational Leadership Team, the individual will also contribute to the overall site goals and vision.

**How you will contribute**:
(60%) Primary responsibilities include:

- Manage all manufacturing improvement activities including:

- Effective and efficient use of the manufacturing and quality systems to allow for routine manufacturing and release of products. These systems include event management-GEMS/ change control-CCMS/ ERP system-JDE /training management
- SABA)
- Ensuring compliance through inter-suite/all manufacturing department alignment
- Timely support for manufacturing batch documentation systems for the operations on the production floor, including Electronic Batch systems
- Align supporting functions to ensure timely start of production and release of product
- Improve work processes and systems within the manufacturing department and cross functionally
- Support the transfer/implementation of new processes and commissioning & validation activities of new projects, as required
- Site overview of production scheduling
- Inculcate a culture of Right First Time for all manufacturing operations
- Escalate and seek alignment for complex investigations, as required
- Work with manufacturing managers to ensure seamless support for operations

(20%) Ad-hoc activities including:

- Front audit requests, manage audit preparation as well as documentation related to audit responses, Adverse Event notification review and Annual Product Reviews, as required
- Develop systems to monitor and analyze processing parameters for atypical trends and improvement opportunities
- Participate in planning activities such as product change over activities or shutdown activities
- Participate in site or above site initiatives

(20%) Team Development and Management:

- Accountable for the hiring and training of new workforce
- Develop the Manufacturing Excellence team into a high performing team, ensuring good team dynamics based on efficient and lean operations
- Communicate key messages and policies to ensure understanding and alignment
- Cultivate a culture that embodies Takeda’s principles and site operational goals
- Carry out performance reviews and talent reviews
- Mentor Manufacturing Excellence, Documentation Supervisors and other team members
- Lead teams in creating a culture that embodies the Takeda Leadership Behaviors
- Ensure team succession is identified, planned and executed
- Responsibility to adhere to any applicable EHS requirements.
- Commitment to a fair and respectful relationship to others and behavior in accordance with Takeda’s Code of Conduct.
- Any other duties as assigned by supervisor.

**What you bring to Takeda**:
**Education and Experience Requirements**
- Education in a relevant discipline, preferably in Biomedical Sciences/Chemical Engineering/Bioengineering /Bio-processing related
- Possess minimum 8 years of relevant experience in the biotechnology, pharmaceutical or chemical processing industry.
- With at least 5 years of management or leadership experience
- Excellent self-motivated team player with hands-on attitude and excellent communication skills
- Experience with product technology transfers and multi-product operations

**Key Skills and Competencies**

The individual should have good understanding of cGMP manufacturing aspects and had hands-on manufacturing experience.
- Leadership experience with management responsibilities
- Excellent knowledge of biopharmaceutical / pharmaceutical plants and unit operations
- Understanding of manufacturing enterprise systems, electronic batch management and have a broad overview of site level interactions
- Knowledge of Lean and/or Six Sigma methodologies
- Excellent trouble shooting, problem solving and communication skills
- Demonstrates high commitment to cGMP, EHS and people development
- Good interpersonal skills and ability to work in a team environment
- Able to understand interactions/ complexity of different manufacturing expertise, for example, Upstream processing/Downstream processing/ Equipment Preparation/ Buffer Preparation
- Demonstrate thorough understanding of various products and their respective processes
- Business acumen
- Demonstrates appropriate level of adaptability, maintains positive outlook, and demonstrates composure under pressure.
- Able