Senior / Research Engineer (Cell Therapy In-vivo

1 day ago

Singapore Singapore-MIT Alliance for Research and Technology Full time

Cell therapy development requires evaluation of efficacy in animal models with well characterized cell sources. Research engineers are key members of the CAMP team who will assist in this essential step of in vivo validation to determine potency of the manufactured cell therapies. The research engineer will work in a team and will receive direct mentorship from post-doctoral associates as well as faculty. The main responsibilities of this position include:

- Conducting daily cell culture activities related to manufacturing of the cell therapy product, e.g., culture media changing, harvesting/sub-culturing of cells, collecting and isolating primary cells of interest from hospitals, etc.
- Run basic diagnostic testing for cultured cells, e.g., flow cytometry, qPCR, differentiation, etc.
- Maintaining a database of information related to cultured cells.
- Management of small rodent animal colonies (Keeping records, checking on health status, etc)
- Assist or when possible, independently perform animal procedures to test potencies of cell therapies. This includes the preparation of animals, performing the procedure and follow-ups as necessary (drug administration, weighing animals, observations, etc., and the keeping of records).
- The collection of data following the in vivo experiment, which includes physical observations, imaging (as needed), collection of tissue specimens at different time points with subsequent processing for analysis. Training will be provided for different analyses.
- Assist or, when appropriate, take charge of the necessary biosafety and ethics record keeping and dissemination.
- Steward all cell culture related equipment and, where appropriate, assist the CAMP Program Manager in training and general CAMP laboratory management activities.

**Job Requirements**:

- Bachelor of Science/Bioengineering degree or Diploma
- Research experience with culturing of mesenchymal or immune cells
- Experience with animal work is highly desirable. Must be comfortable with handling primary human cells and small rodents (mice and rats).
- Good organizational skills and time management
- Experience with basic molecular biology assays and tools for measurement of cellular properties
- Able to work well and communicate ideas effectively in a multidisciplinary team of researchers with different training backgrounds

  • Senior / Research Engineer (Cell Therapy In-vivo

    12 hours ago

    Singapore Singapore-MIT Alliance for Research and Technology Full time

    Cell therapy development requires evaluation of efficacy in animal models with well characterized cell sources. Research engineers are key members of the CAMP team who will assist in this essential step of in vivo validation to determine potency of the manufactured cell therapies. The research engineer will work in a team and will receive direct mentorship...

  • Senior Research Scientist

    4 hours ago

    Singapore beBee Careers Full time

    Cell therapy development involves evaluating efficacy in animal models with well-characterized cell sources.This role requires a Research Engineer to assist in the essential step of in vivo validation, determining the potency of manufactured cell therapies.The engineer will work in a team, receiving direct mentorship from post-doctoral associates and faculty...

  • Director, Cell Therapy Manufacturing Process

    2 weeks ago

    Singapore SCG CELL THERAPY PTE. LTD. Full time

    **About SCG** SCG is a leading biotechnology company focusing on the development of novel immunotherapies in infections and its associated cancers. The company targets the most common cancer-causing infections: helicobacter pylori, HPV, HBV and EBV, and develops a broad and unique pipeline of TCR-based cellular immunotherapy products against...

  • Senior Scientist, TCR-T Cell Therapy

    4 weeks ago

    Singapore NEOCYTOGEN THERAPEUTICS PTE. LTD. Full time

    Roles & ResponsibilitiesNeocytogen therapeutics is a pioneering cell therapy company based in Singapore, dedicated to developing breakthrough immunotherapies to combat cancer. Our mission is to revolutionize the treatment of solid tumors through innovative CAR-NK/TCR-T therapies. Leveraging cutting-edge technologies and a collaborative approach, we aim to...

  • Senior Scientist, TCR-T Cell Therapy

    4 weeks ago

    Singapore NEOCYTOGEN THERAPEUTICS PTE. LTD. Full time

    Roles & ResponsibilitiesNeocytogen therapeutics is a pioneering cell therapy company based in Singapore, dedicated to developing breakthrough immunotherapies to combat cancer. Our mission is to revolutionize the treatment of solid tumors through innovative CAR-NK/TCR-T therapies. Leveraging cutting-edge technologies and a collaborative approach, we aim to...

  • Senior Scientist, TCR-T Cell Therapy

    4 weeks ago

    Singapore NEOCYTOGEN THERAPEUTICS PTE. LTD. Full time

    Roles & ResponsibilitiesNeocytogen therapeutics is a pioneering cell therapy company based in Singapore, dedicated to developing breakthrough immunotherapies to combat cancer. Our mission is to revolutionize the treatment of solid tumors through innovative CAR-NK/TCR-T therapies. Leveraging cutting-edge technologies and a collaborative approach, we aim to...

  • Senior Scientist, TCR-T Cell Therapy

    4 weeks ago

    Singapore NEOCYTOGEN THERAPEUTICS PTE. LTD. Full time

    Roles & ResponsibilitiesWe are a pioneering cell therapy company based in Singapore, dedicated to developing breakthrough immunotherapies to combat cancer. Our mission is to revolutionize the treatment of solid tumors through innovative CAR-NK/TCR-T therapies.The Role:We seek an experienced Scientist to lead and advance our TCR-T cell therapy programs...

  • Cell Manufacturing Specialist

    1 week ago

    Singapore SCG CELL THERAPY PTE. LTD. Full time

    SCG is a leading biotechnology company focusing on the development of novel immunotherapies in infections and its associated cancers. The company targets the most common cancer-causing infections: helicobacter pylori, human papillomavirus, and hepatitis B, and develops a broad and unique pipeline of T cell therapies, antibodies, and therapeutic vaccines...

  • Research Fellow

    2 days ago

    Singapore Nanyang Technological University Full time

    Key Responsibilities: - Design and synthesize novel cell-labeling systems for targeted imaging and therapy in the cancer treatment, including the synthesis and mechanistic studies, intracellular uptake and release studies in vitro, and therapeutic studies in vivo.- A strong research experience in synthetic chemistry and analytical characterizations.- A solid...

  • Senior Cell Therapy Research Specialist

    3 days ago

    Singapore beBee Careers Full time

    Job Title: Senior Research EngineerAbout the RoleWe are seeking a highly motivated and experienced Senior Research Engineer to join our team. The successful candidate will support interdisciplinary projects focused on translating candidate safety Critical Process Parameters (CPPs) to improve the safety of cell therapy products.Key Responsibilities:Routine...