Postdoctoral Research Scientist

6 days ago

Singapore A*STAR Agency for Science, Technology and Research Full time

This position is within the newly established laboratory of Professor Stephen Baker, a globally recognized leader in antimicrobial resistance and bacteriology, The lab's focus is on developing novel therapeutics and preventative strategies against antimicrobial-resistant pathogens and critical infectious diseases.
**Key Responsibilities**:
**Research Leadership**:
Design and lead independent research projects focused on antimicrobial resistance mechanisms and the development of novel therapeutics for combating multidrug-resistant pathogens (e.g., Klebsiella pneumoniae, Escherichia coli).
Investigate molecular pathways to identify novel targets for therapeutic interventions, including small molecules, monoclonal antibodies, and vaccines.
**Data Analysis and Collaboration**:
Analyze complex genomic datasets using bioinformatics tools such as R and Python.
Present findings at international conferences and prepare manuscripts for high-impact journals.
**Therapeutic Development**:
Contribute to the development of next-generation therapeutics, including the evaluation of antimicrobial compounds, immunotherapeutics, and phage-based treatments.
Perform molecular and immunological assays (e.g., ELISA, flow cytometry, protein assays) to test therapeutic efficacy in vitro and in vivo.
**Mentorship and Team Development**:
Mentor junior researchers, including PhD students and research assistants, to foster a collaborative and productive research environment.
Why Join Us?
Develop your independent research career under the mentorship of a globally recognized expert in antimicrobial resistance.
Lead impactful research projects with a focus on developing novel therapeutics.
Publish in leading scientific journals and present at international conferences.
Collaborate with international experts and gain access to state-of-the-art facilities at A*STAR IDL.
Be part of a supportive and ambitious team making a global impact in infectious diseases research.
Job Requirements
PhD in Microbiology, Molecular Biology, Immunology, or a related field, with a strong track record in bacterial genomics or antimicrobial resistance.
Expertise in molecular microbiology and genomic techniques would be an added advantage.
Proven ability to publish in high-impact journals and lead independent research projects.
Expertise in high-throughput genomic technologies (e.g., RNA-seq, TraDIS) and bacterial transcriptomics.
Proficiency in bioinformatics analysis and statistical tools (e.g., R, Python).
Strong molecular microbiology skills, including plasmid conjugation, antimicrobial susceptibility testing, and CRISPR-based tools.
Experience with immunological assays (e.g., flow cytometry) and animal model studies for therapeutic testing.
Knowledge of therapeutic development pipelines, including small molecule and antibody-based interventions.
Excellent mentorship and team leadership capabilities.
Strong written and verbal communication skills for preparing grants, publications, and presentations.
Highly motivated, collaborative, and eager to develop an independent research career.
**Type of Employment**: Full-Time
**Work Location**: Immunos

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