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1 week ago
Job Overview Senior Research Fellow/Research Fellow (Medicine) – The Yong Loo Lin School of Medicine, National University of Singapore. The position is a full-time contract (1 year, renewable) for the Metabolic Liver Disease Lab in the Department of Medicine. Responsibilities Assist the Principal Investigator in coordinating and leading multiple wet lab projects, proposing research directions, and meeting key project milestones. Facilitate research team development and optimize/validate in vitro mammalian cell-based assays related to metabolic diseases (cell culture, RNA/protein extraction, qPCR, western blotting, and other metabolic assays). Perform related duties such as data analysis, ensuring data validity and reliability, maintaining accurate records, and presenting findings to colleagues. Assist with writing for ethics and grant applications. Assist with organizing and publishing findings in high-impact, reputable academic journals. Qualifications A PhD with 3 years of relevant post-doctoral experience. Understanding of molecular/cellular basis of MAFLD, obesity and type 2 diabetes, including lipid metabolism dysregulation, insulin resistance, and inflammatory pathways is desirable. Experience handling 2D and 3D cell cultures (hepatocytes, adipocytes, skeletal muscle cells) is essential. Molecular biology skills (RNA/protein extraction, qPCR, western blotting, immunofluorescence) are essential. Cell line and clinical data multi-omics familiarity (e.g., transcriptomics, proteomics) is a strong plus. Experience with gene perturbation tools (siRNA, shRNA, CRISPR/Cas9) is a strong plus. Experience working with murine models is a strong plus. Excellent writing, communication and presentation skills in English. Highly organized with the ability to work independently and creatively to solve experimental problems within time constraints. Ability to oversee research directions for multiple projects and work in a multidisciplinary team. Location & Organization Location: Kent Ridge Campus Organization: Yong Loo Lin School of Medicine Department: Medicine Employment type: Full-time Job requisition ID: 30222Application Process Applicants should send the following documents by email to and mention “Application for Senior Research Fellow - Metabolic Liver Disease Lab” in the email subject: Cover letter highlighting relevant experience and career goals Curriculum Vitae, including details of three named referees A complete NUS Personal Data Consent for Job Applicants (form available at NUS Personal Data Consent for Job Applicants)Note: Referrals are not required and do not guarantee an interview. #J-18808-Ljbffr
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