Research Fellow

2 weeks ago

Singapore SingHealth Full time

National Cancer Centre of Singapore Pte Ltd

Research Fellow (Ref:DSSOPC-Microbiology)

Job Category: Research

Posting Date: 5 Aug 2025

We are seeking a motivated and enthusiastic postdoctoral Research Fellow to join the Programme in Translational and Clinical Liver Cancer Research, led by Prof Pierce Chow, tenured Professor at Duke-NUS Medical School and NMRC STaR Awardee. Our Program spans the entire spectrum of Liver Cancer scientific investigations from translational research to randomized controlled trials.

A part of the research focuses on an integrative research project focused on understanding the relationship between the gut microbiome and systemic metabolism in liver related metabolic diseases, hepatocellular carcinoma (HCC) progression as well as response to HCC therapies. Utilizing shotgun metagenomic sequencing of stool samples and plasma metabolomics, we aim to identify predictive microbial and metabolic signatures of disease and therapeutic response. The candidate will also have the opportunity to leverage on insights from other omics including bulk tumor next-generation sequencing (NGS), cfDNA NGS, single cell RNAseq and proteomics, CyTOF, 3D spatial transcriptomics and targeted/untargeted metabolomics in the context of a clinical cohort. The next phase involves validating these findings using wet-lab techniques and germ-free or humanised mouse models.

The candidate should be highly motivated with expertise in microbiome-host interactions, microbial culturing, and in vivo functional studies with a focus on the gut-liver axis, host–microbe–tumor interactions, and microbial immunomodulation in liver carcinogenesis to join our interdisciplinary team. The successful candidate will identify potential leads from patient's profiling data, lead experimental validations and contribute to the mechanistic understanding of microbial influence on HCC development or therapeutic response.

The candidate will assist the Principal Investigator in conceptualizing and conducting research projects, responsible for the coordination and management of the microbiome projects of the multidisciplinary study, and to lead grant applications and manuscript preparation.

The successful candidate will thrive in a dynamic and collaborative research environment, working closely with bioinformaticians, clinicians, and researchers involved in ongoing clinical trials. This role offers a unique opportunity to contribute to cutting-edge cancer biology research, with the potential to directly impact therapeutic strategies for HCC patients.

Your responsibilities will include:

  • Design and perform microbiological and molecular biology experiments.
  • Culture and characterize bacterial and/or viral agents implicated in liver disease progression or therapy response.
  • Work with mouse models of HCC, including microbiota-colonized and germ-free systems.
  • Design and execute microbiota

  • Research Fellow

    4 weeks ago

    Singapore Singapore Institute of Technology Full time

    Research Fellow / Engineer (Pharmaceutical Innovation Programme Singapore (PIPS)) - AZN4 Join to apply for the Research Fellow / Engineer (Pharmaceutical Innovation Programme Singapore (PIPS)) - AZN4 role at Singapore Institute of Technology Research Fellow / Engineer (Pharmaceutical Innovation Programme Singapore (PIPS)) - AZN4 1 week ago Be among the...

  • Research Fellow

    2 weeks ago

    Singapore Nanyang Technological University Full time

    Research Fellow / Associate Research Fellow / Senior Analyst / Research Analyst (Military Studies Programme) The S. Rajaratnam School of International Studies (RSIS), a Graduate School of Nanyang Technological University (NTU), is a leading research-intensive and teaching institution in strategic and international affairs and policy-oriented think tank in...

  • Research Fellow

    4 weeks ago

    Singapore NATIONAL UNIVERSITY OF SINGAPORE Full time

    Roles & ResponsibilitiesInterested applicants are invited to apply directly at the NUS Career PortalYour application will be processed only if you apply via NUS Career PortalWe regret that only shortlisted candidates will be notified.Job DescriptionThe Centre for International Law at the National University of Singapore is a university-level research centre,...

  • Research Fellow, Translational Neuroscience, Sics

    2 days ago

    Singapore A*STAR Agency for Science, Technology and Research Full time

    As a research fellow within the program, you will contribute towards SICS and CERES mission, by using novel, age-appropriate digital tools for monitoring and analyzing mental health and wellness in multiple adolescent populations over the course of the peri-pubertal transition. You will also participate in research meetings, training activities, empirical...

  • Research Fellow

    2 weeks ago

    Singapore Cambridge Centre for Advanced Research and Education (CARES) Full time

    **Who are we?** We are the University of Cambridge research centre in Singapore called Cambridge CARES, sponsored by the NRF CREATE program CAM.CREATE. Health-driven design for cities (HD4) is a collaborative research programme between the University of Cambridge, NTU and NUS within Cambridge CARES. HD4 sits at the heart of Singapore’s global research...

  • Research Fellow

    3 weeks ago

    Singapore Nanyang Technological University Singapore Full time

    Research Fellow (Environmental/Chemical Engineering with focus on LCA and LCC analysis) Join to apply for the Research Fellow (Environmental/Chemical Engineering with focus on LCA and LCC analysis) role at Nanyang Technological University Singapore Research Fellow (Environmental/Chemical Engineering with focus on LCA and LCC analysis) 5 days ago Be among...

  • Research Fellow

    2 weeks ago

    Singapore Nanyang Technological University Full time

    The School of Chemistry, Chemical Engineering and Biotechnology (CCEB) invites applications for the position of Research fellow. The Research Fellow will take on a significant role in research. The appointed Research Fellow will synthesize low valent main group compounds featuring an unique electronic structure, and investigate the reactivity. The...

  • Research Fellow

    3 days ago

    Singapore Nanyang Technological University Full time $60,000 - $80,000 per year

    The School of Chemistry, Chemical Engineering and Biotechnology (CCEB) invites applications for the position of Research fellow. The Research Fellow will take on a significant role in research.The appointed Research Fellow will synthesize low valent main group compounds featuring an unique electronic structure, and investigate the reactivity. The reactivity...

  • Research Fellow

    3 weeks ago

    Singapore National University of Singapore Full time

    Research Fellow (Mathematical&Economic Modelling of Infectious Diseases) Join to apply for the Research Fellow (Mathematical&Economic Modelling of Infectious Diseases) role at National University of Singapore Research Fellow (Mathematical&Economic Modelling of Infectious Diseases) 5 days ago Be among the first 25 applicants Join to apply for the Research...

  • Research Fellow

    4 weeks ago

    Singapore Nanyang Technological University Singapore Full time

    Research Fellow (Industrial/Mechanical/Materials Engineering) Join to apply for the Research Fellow (Industrial/Mechanical/Materials Engineering) role at Nanyang Technological University Singapore Research Fellow (Industrial/Mechanical/Materials Engineering) 1 week ago Be among the first 25 applicants Join to apply for the Research Fellow...