Scientist / Senior Scientist, Medicinal Chemistry

3 days ago


Singapore Automera Pte Ltd Full time

Automera is currently seeking an accomplished medicinal chemist to join our innovative team. The successful candidate will be responsible for advancing projects throughout the drug discovery pipeline, from initial hit generation to development candidate selection. This position offers a professional opportunity to contribute meaningfully to the development of innovative therapeutics with potential patient impact. The ideal candidate possesses comprehensive expertise in synthetic and medicinal chemistry, demonstrates strong analytical capabilities, and excels in collaborative endeavours with multidisciplinary scientific teams.
Key Responsibilities:
Design and execute synthetic and medicinal chemistry strategies to meet project goals
Utilize advanced medicinal chemistry expertise to strategically design compounds, incorporating comprehensive analysis of key parameters including potency, selectivity, structure-based drug design, ADME/PK characteristics, and physicochemical properties
Effectively oversee chemistry Contract Research Organizations (CROs) while demonstrating strategic acumen in resource allocation and compound series prioritization
Communicate effectively with cross-functional teams regarding chemistry program strategies, methodologies, and progress updates
Maintain thorough documentation and ensure timely updates to our data management systems
Contribute effectively to patent, report, and scientific publication writing
Qualifications:
Doctorate degree in organic/medicinal chemistry with relevant industry experience and/or postdoctoral research (minimum 2 years), or Master’s degree in organic/medicinal chemistry with substantial hands-on medicinal chemistry expertise (minimum 5 years)
Possesses expertise in synthetic organic chemistry, demonstrating proficiency in analysing complex reaction sequences and interpreting advanced spectroscopic data, including NMR and MS analyses.
Has strong analytical and strategic problem-solving skills to tackle complex challenges
Ability to collaborate across disciplines and integrate cross-functional data to drive medicinal chemistry strategies
Excellent communication and presentation abilities, with skill in conveying technical data to various audiences
Experience in small molecule drug development is essential, with expertise in targeted protein degradation technologies being highly desirable
Experience in overseeing and coordinating synthetic chemistry initiatives with Contract Research Organizations (CROs) would be advantageous
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