Senior Principal Scientist I

1 day ago


Singapore A*STAR RESEARCH ENTITIES Remote Work Freelance Full time

The Institute of Molecular and Cell Biology (IMCB) is seeking an accomplished and visionary scientist to join us as a Principal Investigator in the field of induced pluripotent stem cell (iPSC) modeling and vascular biology . This position is aimed at strengthening IMCB's research in regenerative medicine, disease modeling, and human cell-based systems with relevance to vascular development, function, and disease.We are looking for a principal investigator with a strong international reputation, a track record of scientific leadership, and demonstrated success in securing competitive funding. The successful candidate will lead a high-impact research programme and contribute to IMCB's strategic priorities in advancing human model systems and translational biology.Key Responsibilities Lead an independent research programme in iPSC-based modeling of vascular biology, including endothelial cell development, vascular dysfunction, and vascular contributions to complex diseases Develop novel stem cell-derived platforms for studying human vascular systems and their interactions with other cell types or organs (e.g. brain, liver, tumor microenvironment) Translate disease models into platforms for target discovery, therapeutic screening, or biomarker identification Secure external research funding from national and international sources Supervise and mentor a research team, including students and postdoctoral fellows Build collaborative links with partners across A*STAR, academia, hospitals, and industry Qualifications and Requirements PhD or MD/PhD in Biomedical Sciences, Cell Biology, Developmental Biology, or a related field At least 8-10 years of postdoctoral and/or independent PI experience in stem cell biology, vascular biology, or regenerative medicine Internationally recognised track record of high-impact publications and scientific leadership Proven success in securing competitive research funding and building productive research teams Strong commitment to collaborative, interdisciplinary research and mentoring



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