
CCP Trainee
4 days ago
Lonza is the pioneer and world leader in the CDMO industry operating across 5 continents, setting the pace with cutting-edge science, smart technology and lean manufacturing. We turn our customers’ break-through innovations into viable therapies and manufacture the medicines of tomorrow.
At the heart of every scientific breakthrough are talented individuals collaborating to develop solutions that empower businesses to improve lives. In exchange, we let our people own their careers. Their ideas, big and small, genuinely improve the world. And that’s the kind of work we want to be part of.
As a Biotechnologist at Lonza Cell & Gene Therapy business, you’ll be part of our globally recognized network, driving the production of cell & gene treatments. Join our best-in-class high performance team at our Tuas site in Singapore to gain unparalleled exposure to cutting-edge biotechnology and innovation, and make a difference from day one.
Responsibilities
The Biotechnologist role is responsible for the manufacture of therapeutic cell products under CGMP conditions. Working closely with a team of up to 40 technical, SME and supervisor/manager colleagues, Cell Therapy Biotechnologists are expected to execute CGMP Cell Therapy production activities through to filling of final dose product within a stringent CGMP clean room environment. Production activities occur in the classified production suite which requires change into cleanroom clothing and compliance with clean room standards. This includes removal of jewelry/make-up, donning of over suits/coveralls, safety shoes, shoe covers/booties, hair cover, gloves and safety glasses/shield.
Primary Responsibilities
Complies with site/department EHS standards (policies, rules and regulations).
Attains a thorough understanding of the principles of CGMP compliance and clean room practices.
Contributes to appropriate maintenance of 'in-operation' production facilities and equipment.
Solution and medium preparation followed by aseptic filtration into sterile containers.
Revival and culturing of anchorage dependent cell lines in static flasks and cell factories.
Harvest and concentration of cell factory generated cell cultures using tangential flow filtration or/and centrifugation.
Final formulation and filling of vials. Visual inspection and cryopreservation.
Participation in aseptic process simulations.
Accurate and thorough completion of batch record documentation.
Environmental monitoring (viable particulates, nori-viable particulates, surface and operator).
Formulation of media and aseptic filling of media bags and bottles
Education & Experience
Degree/ Diploma/ NITEC in a related Science/ Engineering discipline
Individual without prior working experience in the biopharmaceutical manufacturing industry is encouraged to apply as training will be provided
Knowledge of cGMP applications
Knowledge of cell culture and the principles of aseptic processing within a classified environment.
Strong team oriented work ethic
Positive team oriented attitude
Strong communication and interpersonal skills
Willing to perform rotating 12-hour shift pattern
Able to perform physical activities in a clean room environment.
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