Research Scientist, ADC Chemistry
1 week ago
About Callio Therapeutics Headquartered in Seattle and Singapore, Callio Therapeutics is focused on realizing the promise of multi-payload antibody-drug conjugates (ADCs) to transform cancer patient outcomes. Significantly backed by the industry’s top investors, the company is developing next-generation, multi-payload ADCs that feature differentiated payload and linker technologies to maximize therapeutic benefit by enabling targeted delivery of multi agents to tumor cells. Callio Therapeutics is focused on driving its HER2-targeted dual-payload ADC to the clinic, gathering key clinical data, and progressing its pipeline assets. About The Role We are looking for a Research Scientist in ADC Chemistry who will work closely with chemistry and ADC team members as well as other cross-functional and external parties, such as CROs. As a Research Scientist in the Chemistry team, you will support the design, making and assessment of linker-payload molecules in our ADCs. Key Responsibilities Participate in the design of molecules, including the identification of synthetic and other potential risks and their mitigations Conduct desk research into molecules and moieties, their properties and impact on ADC profile Prepare reports and other documents on synthetic routes, molecule synthesis, and molecule assessment, with attention-to-detail and data integrity Support administrative and finance activities, including raising and tracking of purchase requests, invoices and budgets Support molecule inventory & supply management, including maintaining of inventories, shipments and supply for ADC manufacture and other activities Support team management activities, including maintaining of activity trackers and dashboards to facilitate team and cross-functional collaboration Qualifications Education & experience: Minimum qualifications: PhD in organic/medicinal chemistry (preferred), alternatively a Masters degree in organic/medicinal chemistry with a minimum of 6 years, predominantly in industry/CRO setting Expertise in the design of pharmaceutical molecules and their synthetic routes Experience in managing administrative activities of a chemistry R&D group, including the tracking of timelines/budgets/activities Experience in preparing reports/experimental write-ups/data summaries Experience working with external parties, such as CROs Experience in chemistry data analysis (HPLC, LC-MS, 1D/2D NMR, etc.)Proficiency with ChemDraw and standard productivity software Familiarity with medicinal chemistry and pharmacology (PK/PD) concepts in oncology as it relates to the design, assessment and iteration of a synthetic campaign Interest and understanding of the current trends and potential challenges in ADC linker-payload synthesis Strong written/oral communication and cross-functional collaboration skills Strong attention-to-detail and ability to quality check data sets What Callio Therapeutics Offers Competitive compensation and comprehensive benefits package Opportunity to work in a dynamic, innovative, and collaborative environment Significantly contribute to potentially groundbreaking therapies for cancer patients For enquiries, please email For more information, please visit and our LinkedIn page #J-18808-Ljbffr
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Research Scientist, ADC Chemistry
2 weeks ago
Singapore Callio Therapeutics Full timeAbout Callio Therapeutics Headquartered in Seattle and Singapore, Callio Therapeutics is focused on realizing the promise of multi-payload antibody-drug conjugates (ADCs) to transform cancer patient outcomes. Significantly backed by the industry’s top investors, the company is developing next-generation, multi-payload ADCs that feature differentiated...
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Research Scientist, ADC Chemistry
19 hours ago
Singapore CALLIO TXS PTE. LTD. Full time $96,000 - $120,000 per yearResearch Scientist, ADC Chemistry – Callio TherapeuticsFull-time position – [Singapore, SG]ABOUT CALLIO THERAPEUTICSHeadquartered in Seattle and Singapore, Callio Therapeutics is focused on realizing the promise of multi-payload antibody-drug conjugates (ADCs) to transform cancer patient outcomes. Significantly backed by the industry's top investors, the...
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Research Scientist, ADC Chemistry
2 weeks ago
Singapore Callio Therapeutics Inc Full timeHeadquartered in Seattle and Singapore, Callio Therapeutics is focused on realizing the promise of multi-payload antibody-drug conjugates (ADCs) to transform cancer patient outcomes. Significantly backed by the industry’s top investors, the company is developing next-generation, multi-payload ADCs that feature differentiated payload and linker technologies...
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Research Scientist
5 days ago
Singapore Hummingbird Bioscience Pte. Ltd Full time**_Opportunity to work at the cutting edge of drug development_** Hummingbird Bioscience is an innovative clinical-stage biotech company focused on developing precision therapies against hard-to-drug targets to improve treatment outcomes. We harness the latest advances in systems biology and data science to better understand and solve the underlying causes...
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Research Scientist
2 weeks ago
Singapore Nanyang Technological University Singapore Full timeJoin to apply for the Research Scientist (Flow Chemistry)role at Nanyang Technological University Singapore 2 days ago Be among the first 25 applicants Join to apply for the Research Scientist (Flow Chemistry)role at Nanyang Technological University Singapore The School of Materials Science and Engineering (MSE) provides a vibrant and nurturing environment...
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Singapore A*STAR - Agency for Science, Technology and Research Full timeScientist/Senior Scientist, Oligonucleotides Chemistry Job Title: Scientist/Senior Scientist, Oligonucleotides Chemistry Organization: Platform Technology Location: Singapore Job Type: Full Time The Nucleic Acid Therapeutics Initiative (NATi), hosted by A*STAR, is Singapore's national platform dedicated to advancing RNA-based medicines and revolutionizing...
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Scientist, Bioconjugation
2 weeks ago
Singapore A*STAR - Agency for Science, Technology and Research Full timeJob Title: Scientist, Bioconjugation & Targeted RNA Delivery Organization: Platform Technology Location: Singapore Job Type: Full Time About NATi: The Nucleic Acid Therapeutics Initiative (NATi), hosted by A*STAR, is Singapore's national platform dedicated to advancing RNA-based medicines and revolutionizing drug and vaccine development. NATi's mission is to...
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(Senior) Research Fellow
1 day ago
Singapore A*STAR Agency for Science, Technology and Research Full timeExperimental Drug Development Center (EDDC) is seeking a highly motivated (Senior) Research Fellow to join the medicinal chemistry department. **As part of the medicinal chemistry team, you will**: Work closely with your supervisor and other senior scientists in medicinal chemistry department as well as other drug discovery disciplines within EDDC Design...
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Research Scientist, Bioinformatics, Ihdp
1 day ago
Singapore A*STAR Agency for Science, Technology and Research Full timeWe are seeking for an enthusiastic and capable computational scientist to help identify protein or metabolite biomarkers of disease risk or treatment response. The scientist will work with an interdisciplinary team of molecular biologists, clinicians, epidemiologists, statisticians and engineers to analyses human data from diverse cohorts. The research will...
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Singapore A*STAR - Agency for Science, Technology and Research Full timeOverview Job Title: Scientist/Senior Scientist, Lipid Nanoparticle Innovation Organization: NATi (Nucleic Acid Therapeutics Initiative), hosted by A*STAR - Agency for Science, Technology and Research Location: Singapore Job Type: Full Time About NATi: The Nucleic Acid Therapeutics Initiative (NATi), hosted by A*STAR, is Singapore's national platform...
