
Research Assistant
3 days ago
Research Assistant (Production Radiochemist)
Join to apply for the
Research Assistant (Production Radiochemist)
role at
National University of Singapore
The National University of Singapore invites applications for
Research Assistant (Production Radiochemist)
in the Clinical Imaging Research Centre (CIRC), Yong Loo Lin School of Medicine. CIRC is a dedicated molecular imaging research centre. It is equipped with on-site capability for the preparation of PET radiopharmaceuticals in a state-of-the-art GMP-certified facility. CIRC supports both academic and commercially led clinical research programs, with dedicated clinical imaging facilities and advanced modalities of PET-CT and PET-MRI. Appointments will be made on a two-years contract basis with the possibility of extension.
Purpose of the post
The Production Radiochemist at CIRC is responsible for the routine production of radiopharmaceuticals inside a Clean Room environment, in compliance with Good Manufacturing Practice (GMP). The Radiochemist will assist in method development and validation of new radiopharmaceuticals, including the preparation of standard operating procedures (SOPs) and other quality documentation. With strong technical and analytical expertise, the Production Radiochemist helps maintain high operational uptime, ensures regulatory compliance, and upholds patient and product safety standards.
Main Duties And Responsibilities
Perform radiolabelling of peptides, antibodies, or small molecules using radionuclides such as Lu-177, Ga-68, F-18, etc.
Prepare and review batch records, lab notebooks, SOPs and other documents.
Assist with emergency maintenance/calibration of radiochemistry synthesis and dispensing modules (e.g., Scintomics, iPhase, Trasis).
Support deviation investigations, CAPAs, and change control implementations as needed.
Perform ad-hoc clean room activities, including cleaning of rooms, stock inventory and environmental monitoring.
Safe handling of radioactive materials including hazardous waste disposal.
Working flexible hours, shifts, or weekends based on production schedules and isotope half-lives.
Performing any other duties as assigned by the Head of Department in accordance with GMP and safety regulations.
Physical Demands and Work Environment
Willing to work with radioactive materials
Able to read, listen and understand technical direction and procedures
Able to lift heavy loads (up to 14 kg with both hands)
Qualifications
Have a minimum of a BSc degree in Synthetic Organic/ Inorganic/ Medical Chemistry or a related science discipline
Practical experiences in general laboratory techniques, such as analytical balance operations, pipetting, pH measurement and reagents preparation
Experiences in pharmaceutical production under Good Manufacturing Practice (GMP) is an added advantage
Experiences in radiolabelling and purification techniques with short-lived radioisotopes (F-18, C-11, Ga-68) or Lu-177 is highly desirable
Proven ability to work independently with minimum supervision as well as a constructive team player
Require critical thinking and problem-solving skills
High attention to detail and commitment to data integrity
Those with no experience but with relevant academic and skills will be considered for this position
Ability to perform first-line troubleshooting and minor repairs on automated modules (e.g., replacing tubing, valves, connectors, heaters)
Ability to read technical manuals, interpret wiring diagrams, and communicate effectively with engineers or vendors for equipment servicing
Remuneration will be commensurate with the candidate’s qualifications and experience. Informal enquiries are welcome and should be made to
Miss Emmalyn Chan Mei Mei
at
.
Formal application : Please submit your application, indicating current/expected salary, supported by a detailed CV (including personal particulars, academic and employment history, complete list of publications/oral presentations and full contacts of three referees to this job portal.
We regret that only shortlisted candidates will be notified.
Location : Kent Ridge Campus
Job requisition details
Organization: Yong Loo Lin School of Medicine
Department: Dean-Med-Clinical Imaging Research Centre
Employee Referral Eligible: No
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