Scientist (LQJ Lab), IMCB

3 days ago


Singapore A*STAR RESEARCH ENTITIES Full time

Dr. Li Qi-Jing's lab is seeking a highly motivated Bioinformatician to join our team. Our research focuses on advancing immunotherapy through cutting-edge cellular and molecular approaches. The successful candidate will play a key role in analyzing high-dimensional datasets, particularly single-cell RNA-seq, ATAC-seq, and spatial transcriptomics, to drive insights into immune cell function. Key Responsibilities: Lead or support analysis of single-cell and bulk RNA sequencing data. Develop and apply pipelines for data integration, clustering, trajectory inference, and gene expression analysis. Collaborate closely with wet-lab scientists to interpret and visualize results. Contribute to experimental design, data interpretation, and manuscript preparation. Maintain and document code, workflows, and datasets for reproducibility. Stay current with new tools, methods, and relevant literature in immunology, oncology, and computational biology. Job Requirements: PhD, or equivalent experience in Bioinformatics, Computational Biology, Systems Biology, or a related field. Proficiency in R and/or Python and/or Perl and/or C++ for data analysis and visualization. Strong experience with single-cell data analysis (e.g., Seurat, Scanpy). Familiarity with data from platforms such as 10x Genomics, CyTOF, or spatial omics. Solid understanding of statistics and machine learning as applied to biological data. Strong communication skills and ability to work collaboratively in a multidisciplinary team. Desirable Skills / Experience: Background in immunology, oncology, or metabolism. Experience working with multi-omics or large-scale clinical datasets. Familiarity with high-performance computing environments and version control (e.g., Git). Previous experience contributing to peer-reviewed publications.



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