Agency for Science, Technology and Research

4 weeks ago


Singapore Agency for Science, Technology and Research (A*STAR) Full time

Host Pathogen Interactions Lab in A*STAR Infectious Diseases Labs (A*STAR IDL) is actively seeking a Scientist to join our mission of becoming a leading center for infectious diseases research. A*STAR IDL is dedicated to advancing translational research in infectious diseases to improve both health and economic outcomes.
Job Description:
We are seeking a talented researcher to lead the research on a 3 year funded research project as well as develop novel ideas in the broad scope of host-pathogen interactions and infectious diseases. Preliminary data gathered will help develop the researcher?s career and path to independence through the various early-career support available internally in A*STAR as well as in the Singapore ecosystem.
The funded project will aim to characterize and compare host-alphavirus interactions at the immune response level in vivo in animal models through a novel viral-centric approach. Preliminary data of the lab has shown a differential adaptive immune response polarization between two alphaviruses and identified, via in vivo comparative multiOmic approaches, a set of candidate host factors potentially responsible for the phenotype. The project will entail a close characterization of these host factors and their role in the viral life cycle as well as the modulation of the immune response of small animal model to these viruses. In addition to multi-Omics approaches (including single-cell and spatial), protein-protein interactions, microscopy, functional genomics, viral reverse genetics and CRISPR Cas9 gene editing will be some of the tools used to investigate this viral hijacking and understand the host-viral interplay. Animals models available in the lab include mice and zebrafish. Downstream of characterization will aim to validate these targets in small preclinical models for subsequent drug discovery in the A*STAR ecosystem. Throughout the project, close collaborative work within A*STAR IDL as well as other institutes throughout Singapore and overseas will be used to leverage expertise for high impact studies.
Job Requirements
PhD in Biomedical Sciences, Life Sciences, Immunology or related field
Atleast 2 years of relevant experience in immunology or related field. No virology experience necessary.
Highly motivated and able to work independently.
Team player with good interpersonal skills.
Good spoken and written communication skills.
Familiar with bioinformatics
Willing to learn to work in a BSL3 facility if necessary
Must be comfortable to work with small animal models.
#J-18808-Ljbffr



  • Singapore Agency for Science, Technology and Research (A*STAR) Full time

    Join the Institute of Microelectronics (IME) to be immersed in cutting-edge semiconductor research. As a research institute within the Agency for Science, Technology and Research (A*STAR), IME bridges the gap between academia and industry. Our mission is to accelerate innovation in advanced packaging, piezoMEMS, SiC, RF/mmwave GaN, and photonics & sensors,...


  • Singapore Agency for Science, Technology and Research (A*STAR) Full time

    JOB DESCRIPTION A*STAR directs and undertakes mission-oriented research to transform Singapore into a knowledge-based and innovation-driven economy. The Research Planning Directorate undertakes the key planning functions for the A*STAR Research Office (RO). Led by the Deputy Chief Executive (Research), the day-to-day operations of RO are managed by...


  • Singapore Agency for Science, Technology and Research (A*STAR) Full time

    About EDDC: EDDC is a National platform dedicated to developing innovative therapies that transform patients' lives. Our research and development efforts are focused on uncovering the underlying mechanisms of disease and translating this knowledge into impactful treatments. We work collaboratively with public sector and industry partners to translate...


  • Singapore Agency for Science, Technology and Research (A*STAR) Full time

    JOB DESCRIPTION The Biomedical Research Council (BMRC)'s mission is to advance the frontiers of bio-sciences and bio-innovations in strategic areas to improve human health and grow our economy. BMRC oversees the development of core research capabilities within A*STAR’s research entities, and actively promotes translational and cross-disciplinary...


  • Singapore Agency for Science, Technology and Research (A*STAR) Full time

    Job Description The Office of Grants Administration serves to provide oversight in grants management and compliance, in order to promote effective stewardship of RIE funds managed by A*STAR either as an Implementing Agency, or a Grant Intermediary. The role of the Assistant Manager/Manager/Senior Manager includes, but is not limited to, the following:...


  • Singapore Agency for Science, Technology and Research (A*STAR) Full time

    The Assistant Manager will be part of a dynamic team, reporting to a Deputy Director (DD) or Senior Assistant Director (SAD), to devise and implement programmes for achieving targeted scientific and economic outcomes. The role includes, but is not limited to, the following: Support the DD/SAD in technology foresighting and strategic R&D planning to catalyse...


  • Singapore Agency for Science, Technology and Research (A*STAR) Full time

    The Institute of High Performance Computing (IHPC) was established in April 1998 to provide leadership in high performance computing as a strategic resource for scientific inquiry and industry development. Our mission is to advance science and technology, and develop leading-edge applications through high performance computing and computational science. We...


  • Singapore Agency for Science, Technology and Research (A*STAR) Full time

    The Institute of High Performance Computing (IHPC) was established in April 1998 to provide leadership in high performance computing as a strategic resource for scientific inquiry and industry development. Our mission is to advance science and technology, and develop leading-edge applications through high performance computing and computational science. We...


  • Singapore Agency for Science, Technology and Research (A*STAR) Full time

    A*STAR Strategic Research and Translational Thrusts (SRTTs) are mission-focused programmes in strategic and emerging areas that are cross-disciplinary and of wider strategic interest to A*STAR and Singapore. Set up to address ambitious technological challenges towards impactful outcomes, each SRTT is led by a Programme Director (PD) and is centrally...


  • Singapore Agency for Science, Technology and Research (A*STAR) Full time

    ISCE2 is seeking a highly motivated Biomanufacturing Scientist to our growing multi-disciplinary team to develop next generation sustainable technology for the biomanufacturing of fine and specialty chemicals. The scientist is responsible for the development and execution of biomanufacturing projects with moderate direct supervision. We are looking for an...


  • Singapore Agency for Science, Technology and Research (A*STAR) Full time

    Account Management and Company Engagements · Point of contact for all agreement related matters. · Drafting of contracts, project related agreements (Research Collaboration Agreement (RCA), etc.) membership agreementsfor review and approval/signature in partnership with A*STAR HQ functions (Legal, I&E, etc.). Industry Outreach · Contract negotiation with...


  • Singapore Agency for Science, Technology and Research (A*STAR) Full time

    As a research institute within the Agency for Science, Technology and Research (A*STAR), IME bridges the gap between academia and industry. Our mission is to accelerate innovation in advanced packaging, piezoMEMS, SiC, RF/mmwave GaN, and photonics & sensors, and to develop talent and inspire in Singapore. We are looking for a highly skilled and experienced...


  • Singapore Agency for Science, Technology and Research (A*STAR) Full time

    The Agency for Science, Technology and Research (A*STAR) is Singapore's lead public sector agency that fosters world-class scientific research and talent to drive economic growth to transform Singapore into a vibrant knowledge-based and innovation driven economy. For more information about A*STAR, please visit: A*STAR is spearheading a series of...


  • Singapore Agency for Science, Technology and Research (A*STAR) Full time

    The Agency for Science, Technology and Research (A*STAR) is Singapore's lead public sector agency that fosters world-class scientific research and talent to drive economic growth to transform Singapore into a vibrant knowledge-based and innovation driven economy. For more information about A*STAR, please visit: A*STAR is spearheading a series of...


  • Singapore Agency for Science, Technology and Research (A*STAR) Full time

    Senior Assistant Director, Research and Statistics Unit,Strategy Directorate A*STAR directs and undertakes mission-oriented research to transform Singapore into a knowledge-based and innovation-driven economy. The Research and Statistics Unit resides in A*STAR'sStrategy Directorate, and spearheads the annual National Survey of Research, Innovation &...


  • Singapore Agency for Science, Technology and Research (A*STAR) Full time

    The A*STAR International Partnerships Office (IPO) is responsible for driving and coordinating A*STAR's international partnerships and engagements in support of A*STAR's mission. Responsibilities: The responsibilities of the Senior Assistant Director (SAD) include: Monitor global trends and risks that may impact on A*STAR's international...


  • Singapore Agency For Science, Technology And Research Full time

    Job Overview: The Deputy Director of the Strategic Planning Team will play a pivotal role in shaping and driving the strategic initiatives of A*STAR Science and Engineering Research. This position requires a dynamic and forward-thinking individual who can work closely with senior leadership to develop and implement strategies that enhance the research and...


  • Singapore Agency for Science, Technology and Research (A*STAR) Full time

    The Advanced Remanufacturing and Technology Centre (ARTC) is a public-private partnership consortium of more than 80 industry members. Our core mission is to develop and deploy advanced manufacturing solutions and upskill the workforce to drive local industry competitiveness. Smart Virtual Systems (SVS) Group is seeking a highly motivated Scientist/ Senior...


  • Singapore Agency for Science, Technology and Research (A*STAR) Full time

    The MedTech Catapult is a national initiative for accelerating the development of high-value MedTech projects through an in-house product engineering unit. The objectives of the Programme Office are to i) support the operations of the MedTech Catapult, ii) develop strategies and seed partnerships to support Catapult activities; and iii) oversee and...


  • Singapore Agency for Science, Technology and Research (A*STAR) Full time

    The Sensory Science and Oral Processing Research Platform at SIFBI seeks to appoint a postdoctoral research scientist to work on the mechanisms of oral-nasal mass transfer and instrumental simulation of the process. Main responsibilities : To conduct independent lab-based research on instrumental design and construction To design experimental devices and...