Biotechnologist 2/3

1 month ago

Singapur, Singapore Lonza Full time
Biotechnologist 2/3 Job Description

At Lonza, we are seeking a highly skilled Biotechnologist 2/3 to join our Manufacturing Team at our Tuas site in Singapore. As a Biotechnologist 2/3, you will be responsible for the manufacturing of therapeutic proteins under cGMP conditions.

Key Responsibilities:
  • Learn and perform well-defined procedures within a GMP manufacturing setting
  • Perform equipment monitoring & basic 6S housekeeping
  • Perform basic laboratory tasks (e.g. sampling, pH/ conductivity/ osmolality measurements etc.)
  • Perform routine sanitization tasks to maintain facility standards
  • Trained & signed off on Performance Measures (PMs) relating to CIP/ SIP/ basic tank & instrument operations
  • Demonstrate aseptic technique in the handling of product/ materials
  • Perform basic process & equipment troubleshooting
  • Multi-task on equipment preparations & operations to ensure adherence to schedule
  • Attain full competency in the performance of all operations relevant to manufacturing areas assigned.
  • Display basic process & equipment troubleshooting ability under routine scenarios.
  • Become a technical process expert by exhibiting basic understanding of critical process/operational parameters and target/acceptable ranges, as well as interactions between different process parameters.
  • Use Standard Operating Procedures (SOPs), logbooks & Batch Records (BRs) effectively & competently
  • Submit samples via Laboratory Information Management System (LIMS)
Cell Culture (Upstream small/ scale)
  • Skill and knowledge of aseptic technique for subculture stages example using culture flask, spinners, wave bioreactors, etc.
  • Technical knowledge on the bioreactor culture control example pH/DO control, CO2/O2 control, cell performance, and metabolites analysis.
Purification (Downstream small scale)
  • Skill and knowledge of column chromatography techniques, tangential flow filtration techniques, micro/Nano filtration techniques, pH/Conductivity adjustment techniques, aseptic techniques.
  • Technical knowledge on the chromatography operating interface example using UNICORN software and various DeltaV control parameters for chromatography and UF operation.
  • Knowledge in single use applications for the respective processes.
Requirements:
  • Degree/Diploma in a related Science/Engineering discipline
  • Some relevant work experience in a similar manufacturing industry or cleanroom environment
  • Knowledge of Biopharmaceutical processing is an added asset
  • Knowledge of cGMP applications
  • Positive team oriented attitude
  • Strong communication and interpersonal skills
  • Willing to perform rotating 12-hour shift pattern

At Lonza, we are committed to improving lives all around the world. We offer a dynamic and challenging work environment where you can grow and develop your skills. If you are a motivated and detail-oriented individual who is passionate about biotechnology, we encourage you to apply for this exciting opportunity.

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