Chief Pharmaceutical Research Specialist

1 week ago

Singapore beBeePharmaceutical Full time $100,000 - $120,000
Research Expert Opportunity

We are seeking a highly motivated Research Fellow to join our team at the Singapore Institute of Technology (SIT). As a University of Applied Learning, SIT works closely with industry in our research pursuits. Our research staff will have the opportunity to be equipped with applied research skill sets that are relevant to industry demands while working on research projects in SIT.

The primary responsibility of this role is to deliver on a Pharmaceutical Innovation Programme Singapore research project where you will be part of a collaborative team exploring innovative ways of understanding extrusion processing for pharmaceutical drug materials and products using rheological measurements.

Main Responsibilities:

  • Characterize mixtures of pharmaceutical excipients and drug materials to develop methodologies for screening hot-melt extrusion formulations and selecting optimal operating conditions using rheology.
  • Validate the developed processing space and operating conditions for extruded pharmaceutical formulations using a lab-scale extruder.
  • Collaborate with researchers at the Singapore-MIT Alliance for Research and Technology (SMART) to characterize the physical properties and performance of intermediate pharmaceutical drug products.

Additional Key Tasks:

  • Participating in and managing the research project with Principal Investigator (PI), and the research team members to ensure all project deliverables are met.
  • Undertaking characterization of pharmaceutical active ingredients, polymeric excipients, and plasticizers for producing amorphous-solid-dispersions.
  • Performing lab-scale hot-melt extrusion of pharmaceutical materials to validate predicted processing conditions and product outcomes.
  • Designing, executing, and interpreting experiments independently.
  • Authoring papers in high-quality journals in areas related to the research.
  • Preparing and delivering reports and presentations for industrial partners.
  • Carrying out Risk Assessment, and ensuring compliance with Work, Safety and Health Regulations.
  • Coordinating procurement and liaising with vendors/suppliers.

Requirements:

  • Having deep hands-on experience with at least one of the areas of polymer rheology, extrusion processing, pharmaceutical engineering with small molecules.
  • Relevant competence in the areas of wet lab work, analytical instrumentation, material science, and formulation.
  • Having an advanced degree in chemical engineering, mechanical engineering, materials science and engineering, or a related field.
  • Knowledge of any of the following will be advantageous: rheology, physical characterization, crystallization, polymer melts, extrusion, material physics.

Key Competencies:

  • Able to build and maintain strong working relationships with people within and external to the university.
  • Self-directed learner who believes in continuous learning and development.
  • Proficient in communicating via technical writing and presentations.
  • Possessing strong analytical and critical thinking skills.
  • Showing strong initiative and taking ownership of work.

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