Cell Culture Specialist

7 days ago

Singapore beBeeBiotechnologist Full time $80,000 - $120,000

As a highly skilled Biotechnologist, you will be part of our globally recognized network driving the production of mammalian cell culture and treatments.

Job Description

This role is responsible for the manufacture of therapeutic cell products under cGMP conditions. You will work closely with a team to execute CGMP Cell Therapy production activities through to filling of final dose product within a stringent clean room environment.

The goal of this position is to develop expert technical knowledge and flawless execution of the Cell Therapy production process. Production activities occur in a classified production suite requiring change into cleanroom clothing and compliance with clean room standards.

This includes removal of jewelry/makeup, donning of over suits/coveralls, safety shoes, shoe covers/booties, hair cover, gloves, and safety glasses/shield. This position offers an ideal opportunity for someone with an interest in Cell Therapy production wanting to develop their production career in a different technical/scientific area.

Thorough training and continual assessment will be provided. After training, successful applicants would be expected to join day, weekend, and public holiday rotation shifts (12 hours).

Responsibilities
  • Complies with site EHS standards.
  • Attains a thorough understanding of the principles of cGMP compliance and clean room practices.
  • Contributes to appropriate maintenance of 'in-operation' production facilities and equipment.

Solution and medium preparation followed by aseptic filtration into sterile containers, revival and culturing of anchorage-dependent cell lines in static flasks and cell factories, harvest and concentration of cell factory-generated cell cultures using tangential flow filtration and/or centrifugation, final formulation and filling of vials, visual inspection and cryopreservation, participation in aseptic process simulations, accurate and thorough completion of batch record documentation, environmental monitoring, formulation of media and aseptic filling of media bags and bottles.

Requirements
  • Degree/Diploma/NITEC in a related Science/Engineering discipline.
  • Individuals without prior experience in biopharmaceutical manufacturing are encouraged to apply as training will be provided.
  • Knowledge of cGMP applications.
  • Knowledge of cell culture and aseptic processing within a classified environment.
  • Strong team-oriented work ethic.
  • Positive team-oriented attitude.
  • Strong communication and interpersonal skills.
  • Willing to perform rotating 12-hour shift patterns.

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