Extrusion Research Scientist

1 week ago

Singapore beBeePharmaceutical Full time $80,000 - $120,000
Job Title:
Rheology and Pharmaceutical Innovation Expert

About the Role:
This position involves working on a research project in pharmaceutical innovation, focusing on extrusion processing for drug materials and products using rheological measurements. The successful candidate will be part of a collaborative team exploring innovative ways to understand and characterize mixtures of pharmaceutical excipients and drug materials.

Responsibilities:
The primary responsibility of this role is to deliver on the research project. This includes characterizing mixtures of pharmaceutical excipients and drug materials, developing methodologies for screening hot-melt extrusion formulations, and selecting optimal operating conditions using rheology. Additionally, the candidate will validate the developed processing space and operating conditions for extruded pharmaceutical formulations using a lab-scale extruder.

Key Responsibilities:
  • Participate in and manage the research project with Principal Investigator (PI), and the research team members to ensure all project deliverables are met.
  • Undertake characterization of pharmaceutical active ingredients, polymeric excipients, and plasticizers for producing amorphous-solid-dispersions.
  • Perform lab-scale hot-melt extrusion of pharmaceutical materials to validate predicted processing conditions and product outcomes.
  • Collaborate with broader pharmaceutical research team at SMART.
  • Design, execute, and interpret experiments independently.
  • Author papers in high-quality journals in areas that are related to the research.
  • Prepare and deliver reports and presentations for industrial partners
  • Carry out Risk Assessment, and ensure compliance with Work, Safety and Health Regulations.
  • Coordinate procurement and liaise with vendors/suppliers.

Requirements:
  • Have deep hands-on experience with at least one of the areas of polymer rheology, extrusion processing, pharmaceutical engineering with small molecules.
  • Relevant competence in the areas of wet lab work, analytical instrumentation, material science and formulation
  • Have an advanced degree in chemical engineering, mechanical engineering, materials science and engineering, or a related field.
  • Knowledge of any of the following will be advantageous: rheology, physical characterisation, crystallisation, polymer melts, extrusion, material physics.

Competencies:
  • Able to build and maintain strong working relationships with people within and external to the organization.
  • Self-directed learner who believes in continuous learning and development.
  • Proficient in communicating via technical writing and presentations.
  • Possess strong analytical and critical thinking skills.
  • Show strong initiative and take ownership of work.

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