Principal Investigator/Cardiovascular Biologist

5 days ago


Singapore beBeeCardioBiology Full time $90,000 - $120,000
Job Title

Senior/Postdoctoral Associate

About the Role

The Singapore MIT Alliance for Research and Technology, Antimicrobial Resistance Interdisciplinary Research Group is seeking a Senior Postdoctoral Associate/Postdoctoral Associate for a project: The pathobiology of tRNA modifications in cardiac development and diseased cell states.

This is a collaborative project with the NUS Yong Loo Lin School of Medicine to map the tRNA epitranscriptome in cardiac cell development and disease states.

The successful candidate will primarily be responsible for leading the project involving RNA epitranscriptomics, nucleic acid, protein sample preparation and molecular/biochemistry work from a variety of cardiac cell and clinical models.

The candidate will utilize and acquire expertise in cardio-biology and multi-omics techniques, and contribute to impactful scientific research.

Key Responsibilities

This role will suit an individual passionate about cardio-biology and omics studies to understand molecular mechanisms of protein translation in heart development and disease.

  • Lead and optimize protocols for mass spectrometry (epitranscriptomics and proteomics), next-gen sequencing (absolute quantification), RNA modification pathway analysis, and various biological processes (i.e. iPSC differentiation)
  • Design experiments to differentiate hiPSCs into cardiac and other cell lineages following established protocols or adapt protocols to answer relevant biological questions that will arise.
  • Collaborate with crossfunctional, crosscultural teammates, the NUS academic/clinical communities, and the wider scientific community.
  • Communicate scientific discoveries through publications, presentations at local and international conferences, and as required in technology disclosure and intellectual property filing.
Requirements

A Ph.D. in a relevant scientific field (e.g., stem cell biology, biotechnology, cell biological engineering or a related discipline) with a good track record of publication and productivity is required.

  • Strong background and hands-on experience in multiomics platforms, next-gen sequencing, and corresponding data analysis is required.
  • Expertise in molecular biology techniques, hiPSC culture, differentiation, characterization techniques is highly desirable.
  • Excellent attention to detail, organizational skills, and ability to maintain accurate and detailed records are essential.
  • Strong communication and the ability to collaborate effectively with cross-functional teams are required.

To apply, please visit our website to submit your full CV/resume, cover letter and list of three references (including reference names and contact information).

We regret that only shortlisted candidates will be notified.



  • Singapore NATIONAL HEART CENTRE OF SINGAPORE PTE LTD Full time

    We are seeking a highly motivated project manager to plan, coordinate and implement collaborated projects. You will be part of the machine learning in cardiovascular imaging team reporting to the Principal Investigator. **Requirements**: - Master or Bachelor Degree in Engineering, Life Sciences or equivalent - 2 years’ experience in project management,...


  • Singapore beBeeCardiovascular Full time $50,000 - $80,000

    Job Title: Cardiovascular Imaging Specialist Are you a skilled healthcare professional looking for a challenging role that leverages your expertise in cardiovascular diagnostics? Do you have experience with echocardiography and a strong passion for delivering high-quality patient care? We are seeking a highly motivated Cardiac Technologist to join our...


  • Singapore beBeeCardiovascular Full time $3,500 - $5,000

    Job Title: Clinical Cardiovascular Specialist">As a Clinical Cardiovascular Specialist, you will play a crucial role in the diagnosis and treatment of cardiovascular diseases. Your primary responsibility will be to conduct routine cardiovascular tests, including echocardiography, treadmill ECG testing, blood pressure monitoring, and Holter monitoring.">The...


  • Singapore beBeeCardiologist Full time $80,000 - $120,000

    Job DescriptionAs a Specialist in cardiovascular medicine, you will be part of a multidisciplinary team at the Department of Cardiology. Your primary responsibility will be to provide day-to-day patient care in the cardiovascular medicine department.You will assist in outpatient and inpatient areas, including invasive and non-invasive investigations and...


  • Singapore beBeeCardiovascular Full time

    Job Title: Clinical Cardiovascular Specialist "> Job Description: ">"> We are seeking a highly skilled Clinical Cardiovascular Specialist to join our team. As a key member of our healthcare staff, you will be responsible for providing high-quality cardiovascular testing and support services. "> You will work closely with doctors and other healthcare...


  • Singapore beBeeCardiovascular Full time $80,000 - $120,000

    Clinical Cardiovascular Specialist Job DescriptionWe are seeking a highly skilled and experienced Clinical Cardiovascular Specialist to join our team.As a key member of our healthcare staff, you will be responsible for providing high-quality cardiovascular testing and support services. You will work closely with doctors and other healthcare professionals to...

  • Molecular Biologist

    4 weeks ago


    Singapore DSO National Laboratories Full time

    Join to apply for the Molecular Biologist role at DSO National Laboratories Continue with Google Continue with Google Join to apply for the Molecular Biologist role at DSO National Laboratories Get AI-powered advice on this job and more exclusive features. Sign in to access AI-powered advices Continue with Google Continue with Google Continue with Google...


  • Singapore Labcorp Full time

    The Principal Investigator (PI) is the primary individual responsible for the preparation, conduct, and administration of the Companion Diagnostic (CDx) research study sponsored by the Pharmaceutical companies and the Diagnostic device manufacturers companies (diagnostic sponsor)_ - The Principal Investigator ensures that good clinical laboratory practices...

  • Research Associate

    3 days ago


    Singapore National University of Singapore Full time

    **Date**:13 Nov 2024 **Location**: SSHSPH, Kent Ridge Campus, SG **Company**:National University of Singapore Applications are invited for the following full-time position in the Saw Swee Hock School of Public Health: A research associate position is available at the Saw Swee Hock School of Public Health to support a principal investigator in...


  • Singapore ESSILOR AMERA PTE. LTD. Full time

    **Position Summary - Purpose and Objectives of the Role This position reports to the Clinical Investigations Team Manager, as part of the Research Institution “Essilor R&D Center Singapore”. The other members part of the Research Institution are Vision Scientists, Principal Investigators, Investigators, Biostatisticians and Data Analysts. Since January...