Senior Production Manager Cell Culture and Purification Lead

4 weeks ago


Singapore CELLVEC PTE. LTD. Full time

We are seeking a Senior Production Manager to lead our Cell Culture and Purification teams at CELLVEC PTE. LTD.

About the Role

The successful candidate will be responsible for overseeing the production of cell-based therapeutics, ensuring timely delivery, and maintaining high-quality standards.

Key Responsibilities:

  • Plan and execute production campaigns within tight timelines.
  • Maintain GMP facilities in a validated state and ensure equipment maintenance, calibration, and requalification.
  • Support validation protocol review and approval.
  • Provide technical expertise for new product introduction, facility fit assessments, FMEA, and change control implementation.
  • Develop and maintain Standard Operating Procedures (SOPs), logbooks, and Batch Manufacturing Records (BMRs).
  • Lead internal and external audits as the spokesperson for the GMP facility and production process.
  • Initiate and close Change Control, Deviations, investigations, and CAPAs.
  • Maintain appropriate staffing levels and skill sets.
  • Foster team dynamics and employee recognition.
  • Ensure safe and compliant working environments.
  • Cultivate a culture of continuous improvement.

Requirements:

  • Degree in a related Science/Engineering discipline.
  • 5-6 years of managerial experience in cell and gene therapy or similar manufacturing industry.
  • Knowledge of Viral Vector manufacturing and Gene Therapy application is an added advantage.
  • Aseptic Manufacturing process knowledge for Drug substance and Drug product is an added advantage.
  • cGMP applications knowledge.
  • Positive team-oriented attitude.
  • Strong communication and interpersonal skills.

Estimated Salary: SGD 120,000 - 180,000 per annum

Benefits:

  • Competitive salary and bonus structure.
  • Comprehensive benefits package including medical, dental, and life insurance.
  • Retirement plan and professional development opportunities.

Others:

  • A unique opportunity to work with a leading biotechnology company.
  • Contribute to the development of innovative cell-based therapeutics.
  • Collaborate with a talented team of professionals.


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