Senior/ Research Scientist

3 weeks ago

Singapore Agency for Science, Technology and Research (A*STAR) Full time

Major responsibilities as a Senior/ Research Scientist in IMCB will include hands-on execution of & disease model development, validation and experiments to evaluate compounds for efficacy in various animal models of diseases with clinically-relevant endpoints, especially with experience to handle rodents.

.Independently responsible for all in vivo work including associated administrative work.

.Responsible for interaction with clients and collaborators for securing, managing and delivery of the projects.

.Responsible for writing and securing grants to support the team.

Requirements:

.PhD Degree in Biological sciences/ Pharmacology or equivalent.

.6-8 years of experience of either academic/industrial preclinical research

.Proficiency and hand on experience in cell culture, molecular biology techniques

.Working knowledge and hands on expertise in pre-clinical / pharmacolog

.toxicology assays and should possess solid understanding of pathophysiology of various diseases

.Well versed with various techniques of rodent animal handling, drug administration by different routes (IV inj, IP inj, SC Inj, IM inj, oral dosing), anaesthesia, rodent surgical techniques, and euthanasia.

.Familiarity with GLP regulations and ICH/FDA guidelines for the conduct of toxicology studies to support regulatory filings.

.Broad understanding of FDA & ICH guidelines.

.Experienced in scientific data compilation, conduct data interpretation, reporting of study results & conclusions, Statistical analysis, Report writing & archiving.

Competencies:

.Excellent communication, interpersonal and leadership skills.

.Experienced in scientific data compilation, conduct data interpretation, reporting of study results & conclusions, Statistical analysis, Report writing & archiving.

.Good working knowledge in scientific and statistical software (Graph pad prism 4.0).

.Good organizational, prioritizing and follow-up skills.

.Ability to write appropriate and relevant SOP's and protocols.

.Ability to handle multiple tasks/projects simultaneously.

.Ability to work well under pressure, with minimal supervision, and to interact with a variety of clients.

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