Research Scientist

1 week ago


Singapore CHUGAI PHARMABODY RESEARCH PTE. LTD. Full time
Chugai Pharmabody Research Pte. Ltd. ("CPR") was establishedin Singapore as a wholly-owned subsidiary of Chugai PharmaceuticalCo., Ltd (Chugai), a member of Roche group, in January 2012 andstarted operations on July 2, 2012. Located at Biopolis inSingapore, it aims to generate newantibody drugs based on Chugai's proprietary antibody engineeringtechnologies, such as recycling antibody, sweeping antibody,bispecific antibody, various Fc engineered antibodies, and othernew antibody engineering technologies that are underdevelopment.

Position - ResearchScientist in Protein Production Unit

CPR is seeking a Scientist with expertise inprotein engineering and producing of various proteins, andexperience of the leading projects of a drug discovery. Thecandidate has strong expertise in protein expression/purification,structure-based protein analysis and/or engineering. The candidatewill be responsible for contributing to novel technologydevelopment and drug discoveryprojects through providingproteins.

JobRequirements
  • Developing efficient methods and strategies forexpressing and purifying difficult-to-handle proteins.
  • Designing proteins for better productivity, stability,activity, etc.
  • Protein expression usingmammalian cell, E.coli, insect cell, or cell-free expressionsystem.
  • Protein purification with columnchromatography (affinity, ion exchange, HIC, size exclusion etc.)using system such as AKTA system.
  • Productionof difficult-to-handle proteins including membrane proteins and/orintracellular proteins so that it can be used for immunization,screening of antibody drug candidates, functional assaysetc.
  • Physicochemical characterization,analysis of proteins and/or structuralanalysis.
The applicant must havecompleted and be awarded with a relevant Master's degree or Ph.Ddegree in science or related field (not in the process of achievingit). The successful candidates must be able to demonstrate theirprotein production and protein engineering expertise as evidencedby projects, presentations, or peer-reviewed scientificpublications.

Scientists with strong passion inmedical science for creating and delivering innovative drugs tosociety which leads to saving patients suffering from unmet medicalneeds are highly desired. As frequent communication and liaison isexpected between both the Singapore and Japan office, you shouldpossess an excellent command of both spoken and written Japanese and English languages, excellentorganizational and communication skills, team player mindset, aswell as the ability to perform multi-task.

Formore information regarding our Company, you may refer to ourwebsite at:

http://chugai-pharmabody.com/

Weregret that only short-listed candidates will benotified
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