research & development lab technician - regenerative medicine

3 weeks ago

Singapore MEDEZE GROUP PTE. LTD. Full time
Roles & Responsibilities

About Us:

Medeze Group Pte Ltd is a pioneering stem cell and tissue engineering company committed to advancing the frontier of tissue engineering and regenerative medicine. Our focus lies in developing groundbreaking solutions to combat the pressing shortage of cornea tissues for transplantation, coupled with innovative approaches to enhance the efficiency of stem cells and cell therapy.

Position Overview: We are seeking a skilled and methodical Lab Technician to join our Research and Development team. This role offers comprehensive training in advanced scaffold fabrication and cell culture techniques, with opportunities to contribute to cutting-edge corneal tissue engineering projects.

Key Responsibilities:

Research Bio Lab technician - Regenerative Medicine Frontiers:

Tissue Engineering and Cell Culture:

  • Support the development of cornea tissues from adult stem cells through specialized cultivation techniques
  • Assist in the fabrication and characterization of collagen-based scaffolds using bovine origin raw material and synthetic polymers
  • Learn and execute scaffold fabrication processes during an intensive 1-2 month training period
  • Participate in the optimization of biomimetic human cornea development using collagen sheets
  • Support animal studies related to corneal tissue engineering

Cellular Expansion Differentiation & Analysis:

  • Assist in cell cultivation, testing, and characterization procedures
  • Prepare and optimize media formulations for cell therapy applications
  • Execute various assays and routine studies with high precision
  • Conduct immunohistological analyses using various techniques on frozen and archived specimens
  • Perform nucleic acid extractions and PCR experiments

Laboratory Operations:

  • Collect, prepare, and evaluate tissue specimens and cultures
  • Maintain and operate sophisticated laboratory equipment
  • Prepare stock solutions, including chemical and radioisotope solutions, following safety protocols
  • Execute immunohistochemistry and immunofluorescence techniques
  • Perform specimen dissection and analysis with precision

Documentation and Quality Control:

  • Record and analyze experimental data using specialized software
  • Perform statistical analysis and maintain detailed documentation
  • Manage laboratory inventory and track calibration schedules
  • Monitor expiration dates and ensure proper material handling
  • Check for up-to-date SOPs on key procedures.
  • Ensure calibrations are performed at appropriate intervals by qualified personnel.
  • Verify proper maintenance of calibration records.
  • Check if a system exists for tracking inventory (chemicals, equipment, consumables).
  • Evaluate the effectiveness of the system in maintaining accurate records.
  • Observe the process of physically counting stock and comparing it to documented records.
  • Ensure discrepancies are identified and addressed appropriately.
  • Review procedures for ordering, receiving, storing, and issuing stock items.
  • Verify proper authorization and documentation for these actions.
  • Assess procedures for tracking expiry dates of chemicals and consumables.
  • Ensure proper disposal methods are followed for expired or hazardous materials.
  • Assist in the acquisition and documentation of reagents and/or consumables.
  • Assist in the maintenance and update of audit-related files.

Qualifications:

  • Diploma or Bachelor's degree in Biological Sciences, Biotechnology, or related field
  • Exposure to laboratory experience
  • Strong expertise in aseptic technique and cell culture
  • Experience with basic molecular biology techniques
  • Excellent documentation and analytical skills
  • Strong attention to detail and ability to follow protocols precisely

Preferred Qualifications:

  • Experience with tissue engineering or biomaterials
  • Knowledge of scaffold fabrication techniques
  • Familiarity with collagen chemistry
  • Experience with immunohistological techniques
  • Background in animal studies

Training Provided:

  • Comprehensive training in scaffold fabrication (1-2 months)
  • Cell culture techniques specific to corneal tissue engineering
  • Handling of specialized equipment and materials
  • Safety protocols for working with biological materials

What We Offer:

  • Training program in advanced tissue engineering techniques
  • Professional development opportunities
  • Collaborative and innovative work environment
  • Opportunity to contribute to groundbreaking medical research

If you are passionate about advancing the frontiers of tissue engineering and regenerative medicine, possess a keen interest in creating biomimetic cornea tissues as well as novel solutions for cell therapy, and are ready to contribute to addressing the cornea shortage crisis, and degenerative tissues, we invite you to apply for the position of Research and Development Lab technician.

Tell employers what skills you have

Cell
Quality Control
Inventory
Immunohistochemistry
Tissue Engineering
Cell Culture
Research and Development
Chemistry
Biotechnology
Medical Research
Molecular Biology
Laboratory
Cell Therapy
Hazardous Materials
Calibration

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