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Manufacturing Biotechnologist

1 month ago

Singapore WUXI XDC SINGAPORE PRIVATE LIMITED Full time
Roles & Responsibilities

Downstream Purification/Bioconjugation Engineer

Work Location: Tuas Biomedical Park

Shift work (including night shift) might be required based on production need

Responsibilities:

  • Bioconjugation reactions and purification of antibody intermediates and conjugated drug substances.
  • Perform downstream protein purification manufacturing operations for drug substances under the guidance of SOPs. This includes, but is not limited to, chromatography system operation, conjugation, low pH viral inactivation operation, nano filtration operation, ultrafiltration washing and filtration operation, and final bulk dispensing.
  • Operate equipment and appliances following the guidance of SOPs and relevant documents.
  • Prepare relevant documents, such as production batch records, SOPs, and validation reports.
  • Communicate and resolve inconsistencies and/or anomalies in production operations.
  • Monitor processes, including real-time review of process parameters, data, and trends.
  • Ensure that the manufacturing operation of drug substances complies with quality and safety regulations.
  • Complete other tasks assigned by superiors.
  • Participate in shift production as required, ensuring compliance with SOP requirements.

Qualifications:

  • Bachelor's degree or above in Biological, Chemical, Pharmaceutical Engineering, or related fields; more than 2 years of experience in antibodies purification or conjugation is preferred.
  • Possess rigorous scientific thinking and habits, with strong execution and planning abilities.
  • Adapt to the GMP cleanroom environment, wearing dust-free clothing, masks, and goggles.
  • Good communication and comprehension abilities.
  • Obey leadership arrangements, demonstrate a hardworking spirit and a positive work attitude.
  • Accept temporary work requirements, such as overtime on weekends or weekdays and other tasks.

Career Development:

  • Through comprehensive systematic training, you will quickly grow into a large-scale cell culture technology expert.
  • Our performance-oriented promotion system and the unique growth incentive plan of the XDS department will help your career development, regardless of your educational background.
  • Explore your management potential, advance alongside a dedicated team, and pave the way for a successful career.

Tell employers what skills you have

Leadership
Bioconjugation
Protein Purification
Ultrafiltration
Chromatography
GMP
Career Development
Cell Culture
Purification
Manufacturing Operations
Compliance
Filtration
Manufacturing
Antibodies