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Production Engineer

4 months ago

Jurong, Singapore GSK Full time

Site Name:
Singapore - Jurong

Posted Date:
Jan


To supervise, execute and monitor the activities within the value stream to ensure reliable and optimal operation of processes, equipment, utility and facility so as to achieve target production levels within the framework of current Good Manufacturing Practice (cGMP), quality, safety, occupational hygiene and environment protection.


_ Responsibilities_:

  • Coordinate with the relevant parties and contribute to the development of the monthly production schedule to enable timely material support to production, and to optimize the production of bulk drug substances so as to minimize holding costs of intermediate goods
  • Assess situation, plan and implement all process campaign turnaround activities, as well as coordinate and track progress of shift teams to ensure production plan adherence.
  • Identify and implement improvement to plant facilities, processes, methods of operations and turnaround, troubleshoot for process and equipment problems to minimize safety and quality risk as well as to ensure greater operational efficiency.
  • Lead or support quality or safety related investigation using appropriate problem solving tool to determine the root causes and implement CAPA to prevent recurrence.
  • Initiate, coordinate, plan and participate in plant modification activities, in the implementation of capital projects, project commissioning and tie in.
  • Conducts audits and investigations, participate in audit preparation and complete identified actions in the assigned work area(s), in order to ensure compliance with GMP and safety requirements.
  • Prepare documents relating to manufacturing, plant turnaround, Local Operating Instructions (LOI), Local Standard Operating Procedures (SOP) and training manual to ensure that updated documents exist to support the activities of the operations department, schedule plan orders, and materials assignment. Documentation should comply to Data Integrity requirements and adherence to ALCOA principles.
  • Provide inputs to Periodic Product Review, Computer System Review and Cleaning Validation Review, Engineering Technical Review
  • Support the Production Manager in new product introduction or plant trials and prepare and complete all necessary documents related to plant trial within the stipulated timeline
- . Participate in the qualification works at OQ and PQ phases
- . Participate in the qualification works at OQ and PQ phases

  • Raise and coordinate change control implementation and follow up on closure of change control.
  • Ensure availability of equipment, tools, production consumables, transfer of input materials as part of campaign preparation and follow up on ensuring housekeeping of above upon campaign ending.

_ Knowledge, Skills & Experience_:

  • Diploma with at least 7 years of relevant experience in pharmaceutical, chemical or petrolchemical industry. OR
  • Good honours degree in Chemistry or Chemical Engineering, with 3 years of relevant experience in pharmaceutical, chemical or petrolchemical industry.
  • Knowledge of product, production processes and the plant
  • Basic engineering knowledge
  • Basic statistical knowledge
  • Good troubleshooting skills
  • Knowledge of GMP, safety, hygiene and environment regulations
  • Basic project management skills
  • Effective communication skills
  • Auditing skills
**_

Why GSK_**:

Uniting science, talent, and technology to get ahead of disease together:
Li-GSK


GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive.

Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years.

Our success absolutely depends on our people.

While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive.

We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be.

A place where they can be themselves - feeling welcome, valued and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

**Important notice to Employment businesses/ Agencies