Research Fellow
4 weeks ago
The School of Chemistry, ChemicalEngineering and Biotechnology (CCEB) invites applications for theposition of Research Fellow in Prof Mary Chan-Park team. Prof MaryChan-Park and her team have recently won a highly competitive largegrant on the design, synthesis and studies of the improved RNAdelivery vehicles.
Prof Mary Chan-Park iscurrently the Centre Director of the Centre for RNA DeliveryTherapeutics. She is also the current President Chair Professor ofChemistry, Chemical Engineering and Biotechnology (2024 onwards)and the 2019 Board of Trustees Chaired Professor of Chemical andBiomedical Engineering (2019-2024), both at the NanyangTechnological University Singapore (NTU Singapore). She also holdsa joint appointment at the Lee Kong Chian School of Medicine atNTU. She is the Director of the Centre for AntimicrobialBioengineering and the Director of the NTU Laboratory for RNADelivery Therapeutics. She is a Fellow of the America Institute ofMedical and Biological Engineering.
The ResearchFellow will take on a significant role to developstimuli-responsive nanoparticle formulations. New alternativedelivery vehicles for the promising RNA nanomedicine are urgentlyneeded to replace the current ones to achieve great deliveryefficacy with less side effects. We have shown that some polymericor lipid nanoparticles are excellent candidates as deliveryagents.
KeyResponsibilities:
- Developnew stimuli-responsive lipid or polymer formulations for RNAnanomedicine to achieve efficient transfection efficiency andendosomal escape.
- Design and synthesize novelcationic or ionizable lipids or polymers for RNAdelivery.
- Formulate lipids/polymers with RNA tocreate delivery systems.
- Measure and evaluatetransfection efficiency, endosomal escape efficiency, and otherparticleproperties
JobRequirements:
- PhD inChemistry, Chemical Engineering, Bioengineering, Materials Science,or related field
- At least 5 years of relevantexperience in stimuli-responsive nanoparticle delivery formulationsand evaluation.
- Familiarity with RNA deliveryformulations (e.g., LNPs) and theirevaluation.
- Proficiency in RNA formulation andRNA evaluation techniques.
- Experience with micestudies and bioimaging (e.g., confocal, FRET,FRAP).
- Strong background in lipid or polymersynthesis.
- Excellent oral and writtencommunication skills; capable of technical leadership andsupervising junior researchers.
- Stronginterpersonal skills, with the ability to work independently, meetdeadlines, and manage timeeffectively.
- Entry-level PhD graduates arewelcome to apply. Recent PhD graduates in chemical engineering,bioengineering, chemistry, materials science, and engineering orrelated fields, with knowledge in RNA delivery and independentresearch, are strongly encouraged to apply orinquire.
We regret thatonly shortlisted candidates will benotified.
Hiring Institution: NTU
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